Mebeverine EP Impurity E CAS 69788-75-6
| CAS No. | 69788-75-6 |
| Molecular Formula | C13H17ClO4 |
| Molecular Weight | 272.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Mebeverine EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Mebeverine EP Impurity E (CAS 69788-75-6, C13H17ClO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Mebeverine EP Impurity E is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 272.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H17ClO4 |
| Molecular Weight | 272.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
Related Mebeverine Standards
- Mebeverine Alcohol-d5 (CAS 2070015-15-3)
- Mebeverine acid D5 (CAS CATO-C4X-168716)
- Mebeverine Acid (CAS 475203-77-1)
- Mebeverine EP Impurity C (CAS 14367-47-6)
- Mebeverine Acid Methyl Ester (CAS 1390154-39-8)
- Mebeverine Impurity 3 (CAS 943723-19-1)
- Mebeverine Hydrochloride EP Impurity D (CAS 93-07-2)
- Mebeverine EP Impurity F (CAS 69788-70-1)
Recommended Standards
- tert-Butyl 2-(4-chloro-2-methoxyphenoxy)acetate (CAS 937817-42-0)
- Esmolol Impurity 46 (CAS 112805-66-0)
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- Esmolol Impurity 94 (CAS CATO-C4X-189194)
- Osimertinib Impurity 65 (CAS CATO-C4X-204565)
- Lenalidomide Impurity 47 (CAS CATO-C4X-190347)
- Oxybutynin Impurity 4 (CAS 4335-77-7)
- cis-4-[2-(3-Bromophenyl)-2-oxoethyl]-cyclohexane-1-carboxylic acid (CAS 735275-56-6)
- (2-Fluoro-5-methylphenyl)methanamine (CAS 93071-82-0)
- N-Diphenylmethyl 2,5-Anhydro-2,5-imino-D-glucitol (CAS 132198-31-3)
- 6-Bromo-5-hydroxypicolinaldehyde (CAS 1273422-87-9)
- (1-((6-Fluoroquinolin-2-yl)methyl)piperidin-4-yl)methanol (CAS 1221411-10-4)
- 3-(2-(Azepan-1-yl)-2-oxoethoxy)benzaldehyde (CAS 943110-46-1)
- (Thr(PO3H2)231)-Tau Peptide (225-237) trifluoroacetate salt (CAS 1670270-09-3)
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