2-Amino-4-chloro-3-nitropyridine CAS 6980-08-1
| CAS No. | 6980-08-1 |
| Molecular Formula | C5H4ClN3O2 |
| Molecular Weight | 173.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Amino-4-chloro-3-nitropyridine (CAS 6980-08-1) is a high-purity analytical reference standard with the molecular formula C5H4ClN3O2 and a molecular weight of 173.56 g/mol.
Structurally, 2-Amino-4-chloro-3-nitropyridine (C5H4ClN3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 173.56 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Amino-4-chloro-3-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4ClN3O2 |
| Molecular Weight | 173.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-6-chloropyrimidine-4-carboxylic acid (CAS 1206249-51-5)
- 5-Amino-3-chloropyrazine-2-carboxylic acid (CAS 1206249-88-8)
- 4-Amino-6-chloropyrimidine-2-carboxylic acid (CAS 1228588-63-3)
- 2-Amino-4-chloropyrimidine-5-carboxylic acid (CAS 1240594-92-6)
- 4-Amino-6-chloropyrimidine-5-carboxylic acid (CAS 1446111-08-5)
- 6-Amino-2-chloropyrimidine-4-carboxylic acid (CAS 16492-29-8)
- 3-Amino-6-chloro-pyridazine-4-carboxylic acid (CAS 1780089-06-6)
- 2-Amino-3-chloro-5-nitropyridine (CAS 22353-35-1)
Recommended Standards
- 2-Amino-4-Chloro-5-Nitropyridine (CAS 24484-96-6)
- 2-(Chloromethyl)-5-nitropyrimidine (CAS 944906-00-7)
- 2-Amino-4-chloro-6-oxo-1,6-dihydropyrimidine-5-carbaldehyde (CAS 85840-20-6)
- 4-Chloro-6-methyl-1,3,5-triazine-2-carboxylic acid (CAS 1956376-15-0)
- 1,2-Di(phenoxymethyl)benzene (CAS 10403-74-4)
- 4,5-Dichloro-2-propylpyridazin-3(2H)-one (CAS 51659-95-1)
- Ethyl 6-methyl-4-(pyridin-3-yl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 123629-47-0)
- 3-(N-(4-chloro-3-methylisoxazol-5-yl)sulfamoyl)-N-methoxy-N-methylthiophene-2-carboxamide (CAS 210421-71-9)
- Tetrahydrofuran-3,4-dicarboxylic acid (CAS 71034-99-6)
- 1-(3-methoxypyridin-2-yl)piperazine dihydrochloride (CAS 1187928-25-1)
- 2-(4-(Trifluoromethoxy)phenyl)acetaldehyde (CAS 111991-22-1)
- Pyridine, 2,6-bis[[2-[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]phenoxy]methyl]- (CAS 850533-59-4)
- 2-(Chloromethyl)-3-((trifluoromethyl)thio)pyridine (CAS 2386232-44-4)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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