Ethyl 2,2-difluoro-2-(m-tolyl)acetate CAS 698379-26-9
| CAS No. | 698379-26-9 |
| Molecular Formula | C11H12F2O2 |
| Molecular Weight | 214.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 214.21 g/mol gives Ethyl 2,2-difluoro-2-(m-tolyl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2,2-difluoro-2-(m-tolyl)acetate (CAS 698379-26-9) is a high-purity analytical reference standard with the molecular formula C11H12F2O2 and a molecular weight of 214.21 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Ethyl 2,2-difluoro-2-(m-tolyl)acetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2,2-difluoro-2-(m-tolyl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12F2O2 |
| Molecular Weight | 214.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Related Ethyl Standards
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Recommended Standards
- Ethyl 2,2-difluoro-(2-methylphenyl)acetate (CAS 698378-71-1)
- Ethyl 3-(2,5-difluorophenyl)propanoate (CAS 959232-75-8)
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- Ethyl 3-(3,4-difluorophenyl)propanoate (CAS 803687-25-4)
- Methyl 3-(4-(5-chloro-2-methylphenyl)piperazine-1-carbothioamido)thiophene-2-carboxylate (CAS 1022580-19-3)
- 4-((4-Methylthiazol-2-yl)thio)butan-1-amine (CAS 1156745-95-7)
- 4,4,6,9-Tetramethyl-6-phenyl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione (CAS 510763-97-0)
- 3-Iodo-5-methoxy-1H-indazole-6-carboxylic acid (CAS 1227267-16-4)
- N-(5,6-Dimethyl-1-propyl-1H-1,3-benzodiazol-4-yl)-3-(trifluoromethyl)benzene-1-sulfonamide (CAS 338423-77-1)
- 2-(Aminomethyl)-3-(difluoromethyl)-6-methoxy-5-(trifluoromethyl)pyridine (CAS 1361901-01-0)
- 2-Bromo-7-iodo-5H-pyrrolo[2,3-b]pyrazine (CAS 875781-44-5)
- 2-(4-(Trifluoromethyl)phenyl)thiazole-5-carbaldehyde (CAS 447406-52-2)
- 2-(chloromethyl)-3-(trifluoromethyl)pyridine hydrochloride (CAS 864264-98-2)
- Neuroendocrine Regulatory Peptide-1 (rat) (CAS 954420-51-0)
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