7-Chloro-2,3-dihydrobenzo[b][1,4]dioxin-5-amine CAS 698985-25-0
| CAS No. | 698985-25-0 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Chloro-2,3-dihydrobenzo[b][1,4]dioxin-5-amine (CAS 698985-25-0), molecular formula C8H8ClNO2 and molecular weight 185.61 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H8ClNO2, 7-Chloro-2,3-dihydrobenzo[b][1,4]dioxin-5-amine contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 185.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 6-Chloro-N,N-dimethylpyrazine-2-carboxamide (CAS 959240-74-5)
- 7-Chloro-2,3-dihydrobenzo[b][1,4]dioxin-6-amine (CAS 855336-74-2)
- 6-Chloro-5-methylpyridin-3-yl acetate (CAS 54232-04-1)
- 8-Chloro-2,3-dihydrobenzo[b][1,4]dioxin-6-amine (CAS 769073-83-8)
- 4-(1-Ethyl-1h-imidazol-5-yl)pyrrolidine-3-carboxylic acid (CAS 1492710-37-8)
- Methyl 1-Benzyl-5-bromopyrazole-3-carboxylate (CAS 1434128-50-3)
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- 2-(4-Methylphenyl)-5-(2-{[(4-methylphenyl)methyl]sulfanyl}phenyl)-1,3,4-oxadiazole (CAS 339104-12-0)
- 2,7-Diazaspiro[4.5]decan-3-one (CAS 1158750-89-0)
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- 5-Bromoindazole-4-carbaldehyde (CAS 1781621-53-1)
- Imidapril Impurity 15 (CAS 157085-06-8(free base))
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
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