3-Chloro-3,3-dimethylbutyrophenone CAS 70048-88-3
| CAS No. | 70048-88-3 |
| Molecular Formula | C12H15ClO |
| Molecular Weight | 210.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-3,3-dimethylbutyrophenone.
CATO supplies 3-Chloro-3,3-dimethylbutyrophenone (CAS 70048-88-3), a certified reference material (molecular formula C12H15ClO, MW 210.70 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-3,3-dimethylbutyrophenone (C12H15ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-3,3-dimethylbutyrophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15ClO |
| Molecular Weight | 210.70 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 1-(4-Chloro-3-methylphenyl)pentan-1-one (CAS 1000370-23-9)
- 1-(3-Chloro-phenyl)-piperidin-4-ylamine (CAS 1048920-62-2)
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Recommended Standards
- 3-Chloro-2-(1-piperidinyl)aniline (CAS 58785-06-1)
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- 4-(4-Chlorophenyl)-4-methylpentan-2-one (CAS 6269-30-3)
- (S)-2-amino-3-(2,3,6-trifluorophenyl)propanoic acid (CAS 873429-60-8)
- N1-(1-(benzofuran-2-yl)ethyl)-N2,N2-diethylethane-1,2-diamine (CAS 1019468-74-6)
- 1-{7-methylthieno[3,2-d]pyrimidin-4-yl}piperazine (CAS 874781-16-5)
- N-(4-(allyloxy)-3-bromo-5-methoxybenzyl)propan-2-amine (CAS 940358-55-4)
- 1-(2-Chloro-5-aminobenzyl)-4-methylpiperazine (CAS 769961-12-8)
- 1-(3-(Aminomethyl)phenyl)-2-(4-fluorophenyl)ethan-1-one hydrochloride (CAS 1187929-08-3)
- Brexpiprazole Impurity 76 HCl (CAS CATO-C4X-113176)
- Ethyl 2-(2-Thiazolyl)acetate (CAS 141704-11-2)
- 5,7-DIbromo-2-methyl-quinolin-8-ylamine (CAS 2104152-51-2)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
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