4-Hydroxy-3-Methylbut-2-enolide CAS 70143-04-3
| CAS No. | 70143-04-3 |
| Molecular Formula | C5H6O3 |
| Molecular Weight | 114.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Hydroxy-3-Methylbut-2-enolide.
CATO supplies 4-Hydroxy-3-Methylbut-2-enolide (CAS 70143-04-3), a certified reference material (molecular formula C5H6O3, MW 114.10 g/mol) for analytical method development and quality control.
The molecular framework of 4-Hydroxy-3-Methylbut-2-enolide (C5H6O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Hydroxy-3-Methylbut-2-enolide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6O3 |
| Molecular Weight | 114.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1977 |
Related Hydroxy Standards
- 4-Hydroxy-3,4-dihydro-2H-pyran-2-one (CAS 112592-82-2)
- 6-Hydroxy-2,3-dihydropyrimidin-4(1H)-one (CAS 112977-56-7)
- (S)-5-Hydroxy-3-methylfuran-2(5H)-one (CAS 1932127-71-3)
- 2-Hydroxy-2-methylbut-3-ynoic acid (CAS 87295-89-4)
- 3-Hydroxy-4-methylfuran-2(5H)-one (CAS 22438-62-6)
- 3-Hydroxy-5-methyl-2(5H)-furanone (CAS 21053-73-6)
- 4-Hydroxy-2,3-dihydropyran-6-one (CAS 55100-07-7)
- 4-hydroxy-3-methyl-2,5-dihydrofuran-2-one (CAS 516-09-6)
Recommended Standards
- 4-Hydroxy-5-methylfuran-2(5H)-one (CAS 36904-76-4)
- 4-Methoxybut-2-ynoic Acid (CAS 24303-64-8)
- 4,5-Dihydrofuran-3-carboxylic Acid (CAS 98021-62-6)
- 5-(Hydroxymethyl)furan-2(3H)-one (CAS 83056-58-0)
- 2-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4-methylaniline (CAS 1036600-97-1)
- 2-(4-(tert-Butyl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol (CAS 22796-15-2)
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- 3-Methyl-1-(piperidin-2-yl)butan-1-ol (CAS 69700-21-6)
- 5-(Bromodifluoromethyl)-2,3-dihydro-1H-1,4-diazepine (CAS 207113-14-2)
- 3-Cyano-4-cyclopropoxy-N-methylpicolinamide (CAS 1243365-16-3)
- 4-(2-(Thiophen-2-yl)ethyl)-1-oxa-4,9-diazaspiro[5.5]undecane (CAS 1708178-94-2)
- N-{6-oxo-4H,5H,6H-cyclopenta[b]thiophen-4-yl}cyclohexanecarboxamide (CAS 865658-99-7)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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