5-(Pyridin-4-yl)-1,3,4-thiadiazol-2-amine hydrochloride CAS 70145-80-1

Description

The occurrence of 5-(Pyridin-4-yl)-1,3,4-thiadiazol-2-amine hydrochloride is closely related to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(Pyridin-4-yl)-1,3,4-thiadiazol-2-amine hydrochloride (CAS 70145-80-1) is a high-purity analytical reference standard with the molecular formula C7H6N4SHCl and a molecular weight of 214.67 g/mol.

Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system, 5-(Pyridin-4-yl)-1,3,4-thiadiazol-2-amine hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 214.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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