(1R,2R)-2-(2,5-difluorophenyl)cyclopropane-1-carboxylic acid CAS 701914-06-9
| CAS No. | 701914-06-9 |
| Molecular Formula | C10H8F2O2 |
| Molecular Weight | 198.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (1R,2R)-2-(2,5-difluorophenyl)cyclopropane-1-carboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (1R,2R)-2-(2,5-difluorophenyl)cyclopropane-1-carboxylic acid (CAS 701914-06-9), a certified reference material (molecular formula C10H8F2O2, MW 198.17 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H8F2O2, (1R,2R)-2-(2,5-difluorophenyl)cyclopropane-1-carboxylic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 198.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1R,2R)-2-(2,5-difluorophenyl)cyclopropane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F2O2 |
| Molecular Weight | 198.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
Recommended Standards
- 4-Methyl-1,3-dihydroisobenzofuran-1,5,6,7-tetraol (CAS 197316-54-4)
- (1R,2R)-2-(2,6-difluorophenyl)cyclopropane-1-carboxylic acid (CAS 455267-88-6)
- Methyl 2,6-Dihydroxy-4-Methoxybenzoate (CAS 19722-76-0)
- (1R,2R)-2-(3,5-difluorophenyl)cyclopropane-1-carboxylic acid (CAS 705250-91-5)
- 1-[3-(Triethoxysilyl)propyl]urea (40-52% in Methanol) (CAS 23779-32-0)
- tert-Butyl 2-isobutylpiperazine-1-carboxylate (CAS 859518-31-3)
- 5-tert-Butyl 2-ethyl 5-azaspiro[3.4]octane-2,5-dicarboxylate (CAS 1251022-90-8)
- Methyl (2R)-2-{[(tert-butoxy)carbonyl](methyl)amino}-4-methylpentanoate (CAS 1820572-12-0)
- Tretinoin Impurity 24 (CAS CATO-C4X-196924)
- 5-[2-methyl-5-(morpholine-4-sulfonyl)phenyl]-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 522624-41-5)
- 1-(3-Bromo-5-fluorobenzyl)-1h-pyrazol-3-amine (CAS 1508707-60-5)
- 4-[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]-2,6-dimethylmorpholine (CAS 646456-36-2)
- 2-Amino-7-bromoquinoline (CAS 116632-53-2)
- Semaglutide impurity 266 (CAS CATO-C4X-2226266)
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