1-(2-Chloro-4-fluorobenzyl)indoline-2,3-dione CAS 701946-42-1

Purity 97%+In StockPharmaceutical Standards
CAS No.701946-42-1
Molecular FormulaC15H9ClFNO2
Molecular Weight289.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-Chloro-4-fluorobenzyl)indoline-2,3-dione CAS 701946-42-1 chemical structure

Description

The occurrence of 1-(2-Chloro-4-fluorobenzyl)indoline-2,3-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(2-Chloro-4-fluorobenzyl)indoline-2,3-dione (CAS 701946-42-1), molecular formula C15H9ClFNO2 and molecular weight 289.69 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 1-(2-Chloro-4-fluorobenzyl)indoline-2,3-dione (C15H9ClFNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 289.69 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2-Chloro-4-fluorobenzyl)indoline-2,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H9ClFNO2
Molecular Weight289.69 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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