N-(5-Chloro-2-methylphenyl)-2,2-diphenylacetamide CAS 70298-73-6
| CAS No. | 70298-73-6 |
| Molecular Formula | C21H18ClNO |
| Molecular Weight | 335.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(5-Chloro-2-methylphenyl)-2,2-diphenylacetamide.
CATO supplies N-(5-Chloro-2-methylphenyl)-2,2-diphenylacetamide (CAS 70298-73-6), a certified reference material (molecular formula C21H18ClNO, MW 335.83 g/mol) for analytical method development and quality control.
N-(5-Chloro-2-methylphenyl)-2,2-diphenylacetamide (C21H18ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H18ClNO |
| Molecular Weight | 335.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 4-Chloro-2,6-bis[(4R)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]pyridine (CAS 1374754-13-8)
- 4-Chloro-2,6-bis[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]pyridine (CAS 142611-36-7)
- 2-Chloro-1-{1-[2-(3,4-dimethoxyphenyl)ethyl]-2,5-dimethyl-1h-pyrrol-3-yl}ethan-1-one (CAS 610274-31-2)
- 2-Chloro-5-(4-hydroxy-3-methyl-2-(methylimino)thiazolidin-4-yl)benzenesulfonamide (CAS 56488-58-5)
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Recommended Standards
- N-(3-Chloro-4-methylphenyl)-2,2-diphenylacetamide (CAS 70298-74-7)
- Tandutinib Impurity 2 (CAS 288383-71-1)
- N-(3-chloro-4-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethan-1-amine (CAS 866038-51-9)
- Tert-Butyl 6-chloro-3-oxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate (CAS 855849-90-0)
- 1-(Pyridin-4-yl)-1H-pyrazole-5-carbaldehyde (CAS 1269293-85-7)
- 4-((3-Chloro-2-hydroxypropyl)amino)benzoic acid (CAS 39083-58-4)
- 1-(1-(4-Fluorophenyl)-1h-pyrazol-4-yl)-N-methylmethanamine hydrochloride (CAS 1255717-50-0)
- Ixazomib Impurity 4 (CAS CATO-C4X-12674)
- 3-Amino-5-(tert-butyl)phenol (CAS 3791-00-2)
- Mupirocin Impurity 30 (CAS 40980-52-7)
- (1E,4E)-1-(4-Isopropylphenyl)-5-phenylpenta-1,4-dien-3-one (CAS 174493-20-0)
- 1-tert-Butyl-4-methyl-1,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one (CAS 1105196-44-8)
- Vortioxetine Impurity 152 (CAS CATO-C4X-1056152)
- Heme iron polypeptide(Hematin) (CAS 14875-96-8)
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