2,5-dioxopyrrolidin-1-yl 1-[2-({4-[(2,5-dioxopyrrolidin-1-yl)oxy]-4-oxobutanoyl}oxy)ethyl] butanedioate 70539-42-3 Di(N-succinimidyl) ethylene glycol disuccinate EGS Ethylene glycol bis(succinimidyl succinate) Ethylene glycol disuccinate di(N-succinimidyl) ester Ethylene glycol-bis[succinimidyl succinate] CAS 70539-42-3
| CAS No. | 70539-42-3 |
| Molecular Formula | C18H20N2O12 |
| Molecular Weight | 456.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,5-dioxopyrrolidin-1-yl 1-[2-({4-[(2,5-dioxopyrrolidin-1-yl)oxy]-4-oxobutanoyl}oxy)ethyl] butanedioate 70539-42-3 Di(N-succinimidyl) ethylene glycol disuccinate EGS Ethylene glycol bis(succinimidyl succinate) Ethylene glycol disuccinate di(N-succinimidyl) ester Ethylene glycol-bis[succinimidyl succinate] is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2,5-dioxopyrrolidin-1-yl 1-[2-({4-[(2,5-dioxopyrrolidin-1-yl)oxy]-4-oxobutanoyl}oxy)ethyl] butanedioate 70539-42-3 Di(N-succinimidyl) ethylene glycol disuccinate EGS Ethylene glycol bis(succinimidyl succinate) Ethylene glycol disuccinate di(N-succinimidyl) ester Ethylene glycol-bis[succinimidyl succinate] (CAS 70539-42-3), a certified reference material (molecular formula C18H20N2O12, MW 456.36 g/mol) for analytical method development and quality control.
Structurally, 2,5-dioxopyrrolidin-1-yl 1-[2-({4-[(2,5-dioxopyrrolidin-1-yl)oxy]-4-oxobutanoyl}oxy)ethyl] butanedioate 70539-42-3 Di(N-succinimidyl) ethylene glycol disuccinate EGS Ethylene glycol bis(succinimidyl succinate) Ethylene glycol disuccinate di(N-succinimidyl) ester Ethylene glycol-bis[succinimidyl succinate] (C18H20N2O12) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 456.36 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O12 |
| Molecular Weight | 456.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 2 |
Related dioxopyrrolidin Standards
- 2,5-Dioxopyrrolidin-1-yl 3-(2-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)propanoate (CAS 1260092-31-6)
- 2,5-Dioxopyrrolidin-1-yl 6-(5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoate (CAS 1219212-66-4)
- 2,5-Dioxopyrrolidin-1-yl 6-((7-(N,N-dimethylsulfamoyl)benzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoate (CAS 1858255-08-9)
- 2,5-Dioxopyrrolidin-1-yl 6-((6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)amino)-6-oxohexanoate (CAS 1934284-26-0)
- (E)-2,5-Dioxopyrrolidin-1-yl 17-bromo-4,7,10,13-tetraoxaheptadec-15-en-1-oate (CAS 1283658-84-3)
- 3-(2,5-Dioxopyrrolidin-1-yl)-N-(4-(7-ethoxybenzofuran-2-yl)thiazol-2-yl)benzamide (CAS 921570-18-5)
- 2,5-Dioxopyrrolidin-1-yl 6-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)hexanoate (CAS 125697-63-4)
- 2,5-Dioxopyrrolidin-1-yl (S)-2-(((benzyloxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoate (CAS 116115-11-8)
Recommended Standards
- tert-butyl 1-benzyl-3-iodo-1,8-diazaspiro[4.5]decane-8-carboxylate (CAS 2177264-11-6)
- (2S,4S)-4-[2-Bromo-4-(tert-pentyl)phenoxy]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid (CAS 1354484-72-2)
- 4-Bromobenzyl (4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridin-2-yl)carbamate (CAS 672950-52-6)
- 6-Chloro-7-[4-(4-chlorobenzyl)-1-piperazinyl]-2-(1,3-dimethyl-4-pyrazolyl)-3H-imidazo[4,5-b]pyridine (CAS 1402709-93-6)
- Tert-butyl (6-(hydroxymethyl)piperidin-3-yl)carbamate (CAS 1150618-40-8)
- (S)-2-(2-(1H-Indol-3-yl)acetamido)-3-methylbutanoic acid (CAS 57105-42-7)
- Benzo[d]isoxazol-5-ol (CAS 808755-45-5)
- (R)-6-Methoxychroman-3-carboxylic acid (CAS 182570-27-0)
- 6-Chloro-4-methylpyridin-2-ol (CAS 25297-47-6)
- 5-Hexanoyl-2,2-dimethylcyclopentan-1-one (CAS 1540837-58-8)
- 4-Methyl-N-(2,2,2-trifluoro-1-(pyridin-4-yl)ethyl)benzenesulfonamide (CAS 851165-68-9)
- 2-(5-Ethoxy-1-methyl-2,4-dioxo-1,4-dihydropyrido[2,3-d]pyrimidin-3(2H)-yl)-N-(2-methoxyethyl)acetamide (CAS 941898-42-6)
- 2-Formylthiophene-4-boronic acid (CAS 175592-59-3)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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