Ethyl 4-hydroxy-2-phenylthiazole-5-carboxylate CAS 70547-29-4

Purity 97%+In StockPharmaceutical Standards
CAS No.70547-29-4
Molecular FormulaC12H11NO3S
Molecular Weight249.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 4-hydroxy-2-phenylthiazole-5-carboxylate CAS 70547-29-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 249.29 g/mol gives Ethyl 4-hydroxy-2-phenylthiazole-5-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ethyl 4-hydroxy-2-phenylthiazole-5-carboxylate (CAS 70547-29-4), molecular formula C12H11NO3S and molecular weight 249.29 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Ethyl 4-hydroxy-2-phenylthiazole-5-carboxylate (C12H11NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H11NO3S
Molecular Weight249.29 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1977
Nitrogen Atoms1
Sulfur Atoms1

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