6-Chloro-3,4-dihydro-2H-1,4-benzoxazine CAS 70558-11-1
| CAS No. | 70558-11-1 |
| Molecular Formula | C8H8ClNO |
| Molecular Weight | 169.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Chloro-3,4-dihydro-2H-1,4-benzoxazine (CAS 70558-11-1), a certified reference material (molecular formula C8H8ClNO, MW 169.61 g/mol) for analytical method development and quality control.
6-Chloro-3,4-dihydro-2H-1,4-benzoxazine (C8H8ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-3,4-dihydro-2H-1,4-benzoxazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO |
| Molecular Weight | 169.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(4-Chloro-3,5-dimethyl-1H-pyrazol-1-yl)acetonitrile (CAS 1004643-52-0)
- 3-(4-Chloro-1h-pyrazol-1-yl)-2-methylpropanenitrile (CAS 1006328-60-4)
- 3-(4-Chloro-1h-pyrazol-1-yl)butanenitrile (CAS 1006333-97-6)
- 3-(4-Chloro-3-methyl-1h-pyrazol-1-yl)propanenitrile (CAS 1006508-15-1)
- 2-Chloro-5-methylbenzamide (CAS 101080-00-6)
- 2-Chloro-6-methylbenzamide (CAS 101080-58-4)
- N-(2-Chloro-6-methylphenyl)formamide (CAS 10113-37-8)
- 1-(5-Chloro-6-methylpyridin-3-yl)ethan-1-one (CAS 1011470-12-4)
Recommended Standards
- 6-Chloro-2,3-dihydrobenzofuran-3-amine (CAS 944899-93-8)
- 6-chloro-N-cyclopropylpyridazin-3-amine (CAS 941294-45-7)
- 6-Chloro-1,3-dihydroisobenzofuran-5-amine (CAS 2304496-03-3)
- 6-Chloro-N-cyclopropylpyrimidin-4-amine (CAS 941294-43-5)
- 1-(3-Fluoro-4-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 1443346-00-6)
- [13C]-9-Methylfluorene-9-carboxylic acid (CAS 1285695-14-8)
- 4,5-Dihydroxyisobenzofuran-1,3-dione (CAS 116314-76-2)
- 3-Hydroxy-3-(pyridin-3-yl)propanoic acid (CAS 1251358-19-6)
- 3-Chloro-6-hydroxypyridine-2-carboxylic Acid (CAS 1263280-37-0)
- 4-Butylbiphenyl (CAS 37909-95-8)
- 2-{2-azabicyclo[2.2.1]heptan-2-yl}ethan-1-amine (CAS 878155-47-6)
- 5-Bromo-3-cyano-2-methoxybenzoic acid (CAS 1805101-65-8)
- 3,3'-Disulfanediylbis(4-aminobenzenesulfonamide) (CAS 5332-71-8)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
Why CATO?
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