8-Fluoro-6-methoxyquinolin-4-ol CAS 706809-34-9
| CAS No. | 706809-34-9 |
| Molecular Formula | C10H8FNO2 |
| Molecular Weight | 193.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 8-Fluoro-6-methoxyquinolin-4-ol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 193.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
8-Fluoro-6-methoxyquinolin-4-ol (CAS 706809-34-9) is a high-purity analytical reference standard with the molecular formula C10H8FNO2 and a molecular weight of 193.17 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Fluoro-6-methoxyquinolin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8FNO2 |
| Molecular Weight | 193.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 7-Fluoro-3-(Hydroxymethyl)-1,2-dihydroquinolin-2-one (CAS 1017386-68-3)
- 2-(6-Fluoro-2,4-dihydro-1,3-benzodioxin-8-yl)acetonitrile (CAS 1087784-38-0)
- Methyl 4-Fluoro-1H-indole-2-carboxylate (CAS 113162-36-0)
- 4-Fluoro-1-methyl-1h-indole-2-carboxylic acid (CAS 1146291-81-7)
- Methyl 7-fluoro-1H-indole-2-carboxylate (CAS 1158331-26-0)
- 6-Fluoro-4-methoxyquinolin-2-ol (CAS 1196155-78-8)
- 4-Fluoro-5-methoxyindole-3-carboxaldehyde (CAS 1227563-28-1)
- 4-Fluoro-6-methoxy-indole-3-carboxyaldehyde (CAS 1227573-88-7)
Recommended Standards
- 8-Fluoro-6-methoxyisoquinolin-1-ol (CAS 2088942-78-1)
- Ethyl 3-(6-fluoropyridin-3-yl)propiolate (CAS 2797070-35-8)
- 7-Fluoro-6-methoxyquinolin-4(1H)-one (CAS 948573-52-2)
- Ethyl 3-cyano-4-fluorobenzoate (CAS 773136-57-5)
- 1-(7-Bromo-1H-indazol-1-yl)ethan-1-one (CAS 1158680-87-5)
- 1-Cyclobutylethane-1,2-diamine (CAS 1270470-80-8)
- 3-(Ethylcarbamoyl)-1,3-thiazolidine-4-carboxylic acid (CAS 1008385-67-8)
- 3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-(pyrrolidin-1-yl)benzene-1-sulfonamide (CAS 794572-10-4)
- 1’-Oxo Perazine (CAS 91508-47-3)
- [13C,2H3]-Sorafenib (CAS 1210608-86-8)
- 6-Isopropyl-3-propylbenzo[d]thiazol-2(3H)-imine hydroiodide (CAS 2034157-24-7)
- Ethyl 8-bromo-6-cyano-4-hydroxyquinoline-3-carboxylate (CAS 1233518-56-3)
- 1-(Tert-butyl)-3-ethyl-1H-pyrazole-4-carboxylic acid (CAS 682757-48-8)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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