4-Chloro-2-methyl-1-(trifluoromethoxy)benzene CAS 70692-44-3
| CAS No. | 70692-44-3 |
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-methyl-1-(trifluoromethoxy)benzene (CAS 70692-44-3) is a high-purity analytical reference standard with the molecular formula C8H6ClF3O and a molecular weight of 210.58 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 4-Chloro-2-methyl-1-(trifluoromethoxy)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 210.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-2-methyl-1-(trifluoromethoxy)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3O |
| Molecular Weight | 210.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (2-Chloro-6-(trifluoromethyl)pyridin-4-yl)methanamine (CAS 1060810-25-4)
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- 1-Chloro-3-(2,2,2-trifluoroethoxy)benzene (CAS 106854-78-8)
- (4-Chloro-6-(trifluoromethyl)pyridin-2-yl)methanamine (CAS 1196154-09-2)
- S 2-Chloro-1-(2,3,4-trifluoro-phenyl)-ethanol 1204756-51-3 A1-02931 (CAS 1204756-51-3)
- 6-Chloro-N-methyl-4-(trifluoromethyl)pyridin-2-amine (CAS 1208081-32-6)
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Recommended Standards
- 4-Chloro-2,6-dimethyl-5-(trifluoromethyl)pyrimidine (CAS 2417423-28-8)
- 4-Chloro-5-cyclopropyl -3-(trifluoromethyl)-1H-Pyrazole (CAS 740807-81-2)
- 4-Chloro-2-(trifluoromethyl)benzyl alcohol (CAS 773872-13-2)
- 4-Chloro-6-methyl-5-(trifluoromethyl)pyridin-2-amine (CAS 2852767-61-2)
- [(2-methoxy-4,6-dimethylpyridin-3-yl)methyl](methyl)amine (CAS 1249806-32-3)
- 3-(bromomethyl)-2-methoxy-5-(trifluoromethyl)pyridine (CAS 1227576-08-0)
- 1-Butyl-3-methyl-1H-imidazol-3-ium hydrogen carbonate (CAS 366491-15-8)
- tert-Butyl 4-hydroxy-2-oxo-5,6,8,9-tetrahydro-1H-pyrido[2,3-d]azepine-7(2H)-carboxylate (CAS 959636-64-7)
- 1,3-Propanediamine, N1-(3-aminopropyl)-, polymer with 2-(chloromethyl)oxirane (CAS 51961-45-6)
- 2-[Methyl(3-pyrrolidinyl)amino]-1-ethanoldihydrochloride (CAS 1219957-28-4)
- (S)-4-Amino-4-oxo-2-((2-sulfoethyl)amino)butanoic acid (CAS 116709-49-0)
- 7-Bromo-2-chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 1936463-54-5)
- Rimegepant Impurity 94 (CAS CATO-C4X-248794)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com