2-Chloro-4-(trifluoromethoxy)phenol CAS 70783-75-4
| CAS No. | 70783-75-4 |
| Molecular Formula | C7H4ClF3O2 |
| Molecular Weight | 212.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloro-4-(trifluoromethoxy)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloro-4-(trifluoromethoxy)phenol (CAS 70783-75-4), molecular formula C7H4ClF3O2 and molecular weight 212.55 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-4-(trifluoromethoxy)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 212.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3O2 |
| Molecular Weight | 212.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-4-(trifluoromethoxy)phenol (CAS 1000339-94-5)
- 3-Chloro-5-(trifluoromethoxy)phenol (CAS 1017778-52-7)
- 2-Chloro-6-(trifluoromethoxy)phenol (CAS 1036713-42-4)
- 5-Chloro-2-(trifluoromethoxy)phenol (CAS 1092461-24-9)
- 3-CHloro-2-(trifluoromethoxy)phenol (CAS 1261878-39-0)
- 2-Chloro-5-(trifluoromethoxy)phenol (CAS 139625-85-7)
- 4-Chloro-3-(trifluoromethoxy)phenol (CAS 886500-85-2)
- 2-Chloro-6-(2,2,2-trifluoroethoxy)pyrazine (CAS 1016530-98-5)
Recommended Standards
- 5-Methyl-2-(trifluoromethyl)-3-furoyl chloride (CAS 175276-66-1)
- 2-Chloro-3-(trifluoromethoxy)pyridin-4-amine (CAS 1221171-79-4)
- 2-Chloro-6-(trifluoromethoxy)pyridin-4-amine (CAS 1221171-99-8)
- 2-(Chloromethyl)-6-(trifluoromethyl)pyrimidin-4-ol (CAS 1240596-45-5)
- 1-(3-Methoxybenzoyl)piperazine (CAS 100939-89-7)
- 5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)-N-(3-methoxyphenyl)thiophene-2-sulfonamide (CAS 306976-59-0)
- Ethyl 5-acetoxy-2,5-dimethyl-4-oxo-4,5-dihydrofuran-3-carboxylate (CAS 53252-54-3)
- Cyclopropyl(4-(trifluoromethyl)phenyl)methanamine hydrochloride (CAS 1159825-60-1)
- tert-Butyl 4-[cyano(phenyl)methyl]piperazine-1-carboxylate (CAS 444891-21-8)
- endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-amine (CAS 87571-88-8)
- 1,2,3,4-Tetrafluoroanthracene (CAS 102936-13-0)
- 3-(2,5-Difluorobenzyl)azetidine (CAS 1096295-76-9)
- 5-(Benzyloxy)-4-bromo-2-(tert-butyl)aniline (CAS 2802468-19-3)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
Why CATO?
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