(4-Benzoylpiperazin-1-yl)(3-chlorophenyl)methanone CAS 708981-95-7

Purity 97%+In StockPharmaceutical Standards
CAS No.708981-95-7
Molecular FormulaC18H17ClN2O2
Molecular Weight328.79 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(4-Benzoylpiperazin-1-yl)(3-chlorophenyl)methanone CAS 708981-95-7 chemical structure

Description

The molecular framework of (4-Benzoylpiperazin-1-yl)(3-chlorophenyl)methanone (C18H17ClN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

(4-Benzoylpiperazin-1-yl)(3-chlorophenyl)methanone (CAS 708981-95-7), molecular formula C18H17ClN2O2 and molecular weight 328.79 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H17ClN2O2
Molecular Weight328.79 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentCl-containing
Nitrogen Atoms2

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