3,5-Bis(trifluoromethyl)-4H-1,2,4-triazole CAS 709-62-6

Purity 97%+In StockPharmaceutical Standards
CAS No.709-62-6
Molecular FormulaC4HF6N3
Molecular Weight205.06 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,5-Bis(trifluoromethyl)-4H-1,2,4-triazole CAS 709-62-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 205.06 g/mol gives 3,5-Bis(trifluoromethyl)-4H-1,2,4-triazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3,5-Bis(trifluoromethyl)-4H-1,2,4-triazole (CAS 709-62-6), a certified reference material (molecular formula C4HF6N3, MW 205.06 g/mol) for analytical method development and quality control.

The molecular framework of 3,5-Bis(trifluoromethyl)-4H-1,2,4-triazole (C4HF6N3) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3,5-Bis(trifluoromethyl)-4H-1,2,4-triazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC4HF6N3
Molecular Weight205.06 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms3

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