2-(4-fluoro-2-iodophenyl)acetic acid CAS 70931-61-2
| CAS No. | 70931-61-2 |
| Molecular Formula | C8H6FIO2 |
| Molecular Weight | 280.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-fluoro-2-iodophenyl)acetic acid.
2-(4-fluoro-2-iodophenyl)acetic acid (CAS 70931-61-2) is a high-purity analytical reference standard with the molecular formula C8H6FIO2 and a molecular weight of 280.03 g/mol.
The molecular framework of 2-(4-fluoro-2-iodophenyl)acetic acid (C8H6FIO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6FIO2 |
| Molecular Weight | 280.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F/I-containing |
Related fluoro Standards
- 4-Fluoro-2-iodo-6-methylbenzoic acid (CAS 1048025-60-0)
- Methyl 4-fluoro-3-iodobenzoate (CAS 1121586-29-5)
- 6-Fluoro-3-iodo-2-methylbenzoic Acid (CAS 1149379-03-2)
- Methyl 5-Fluoro-2-iodobenzoate (CAS 1202897-48-0)
- Methyl 2-fluoro-3-iodobenzoate (CAS 1260830-14-5)
- Methyl 3-fluoro-5-iodobenzoate (CAS 1261478-09-4)
- 2-(3-Fluoro-4-iodophenyl)acetic acid (CAS 1261874-58-1)
- 2-Fluoro-5-iodo-4-methylbenzoic Acid (CAS 1300741-56-3)
Recommended Standards
- 2-(2-Fluoro-4-iodophenyl)acetic acid (CAS 345963-96-4)
- 2-Fluoro-2-(4-iodophenyl)acetic acid (CAS 2760975-40-2)
- 4-Fluoro-5-iodo-2-methylbenzoic acid (CAS 1533441-18-7)
- 2-Fluoro-3-iodo-4-methoxybenzaldehyde (CAS 2365419-30-1)
- Lithium Difluoroacetate (CAS 74956-94-8)
- 3-Iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1138443-83-0)
- 2-Amino-N-methyl-N-(pyridin-2-ylmethyl)butanamide (CAS 1218614-30-2)
- (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-3-(1H-indol-4-yl)propanoic acid (CAS 1251904-20-7)
- 1-(2-Amino-2-methylpropyl)-N,N-dimethylpiperidin-4-amine (CAS 1197398-82-5)
- 5-(4-Chlorophenyl)-1-(2-propylpentanoyl)pyrazolidin-3-one (CAS 740812-30-0)
- 2-(Benzo[d][1,3]dioxol-5-yl)-N-(5-methylisoxazol-3-yl)acetamide (CAS 922557-08-2)
- Rasagiline Impurity 5 (CAS 68253-35-0)
- 2-Bromo-8-(3-chlorophenoxy)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridine (CAS 2443488-31-9)
- Semaglutide impurity 31 (CAS CATO-C4X-222631)
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