(2-Trifluoromethyl-[1,3]dioxolan-2-yl)-acetic acid CAS 70976-13-5
| CAS No. | 70976-13-5 |
| Molecular Formula | C6H7F3O4 |
| Molecular Weight | 200.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2-Trifluoromethyl-[1,3]dioxolan-2-yl)-acetic acid.
CATO supplies (2-Trifluoromethyl-[1,3]dioxolan-2-yl)-acetic acid (CAS 70976-13-5), a certified reference material (molecular formula C6H7F3O4, MW 200.11 g/mol) for analytical method development and quality control.
The molecular framework of (2-Trifluoromethyl-[1,3]dioxolan-2-yl)-acetic acid (C6H7F3O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7F3O4 |
| Molecular Weight | 200.11 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)malonic acid dimethyl ester (CAS 5838-00-6)
- 3-(Trifluoromethyl)pentanedioic acid (CAS 4162-55-4)
- 2-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]acetic acid (CAS 1369240-90-3)
- 7-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-one (CAS 1003048-68-7)
- 3-Methyl-2-(trifluoromethyl)benzofuran (CAS 1099598-16-9)
- 3-Methyl-7-(trifluoromethyl)-2h-indazole (CAS 1108623-64-8)
- 3-(Trifluoromethyl)-1H-indol-6-amine (CAS 1132668-54-2)
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Recommended Standards
- 1H-Pyrazole-3,4,5-tricarboxylic acid (CAS 19551-66-7)
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- 3-(3,4,5-Trifluorophenyl)propiolic acid (CAS 1341759-68-9)
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- 3-Bromo-5-fluoro-4-methoxyaniline (CAS 875664-44-1)
- 2-Chloro-6-methoxypyridine-4-boronic acid (CAS 2121512-97-6)
- (2S,3S,4S,5S,6S)-3,4,5-Trihydroxy-6-methoxytetrahydro-2H-pyran-2-carboxylic acid (CAS 5391-16-2)
- 4-(2-ethoxyethyl)piperidine (CAS 509147-81-3)
- 6-Chlorofuro[3,2-b]pyridine (CAS 1142192-61-7)
- 5-cyclopropyl-1H-1,2,4-triazole-3-carboxamide (CAS 1502673-73-5)
- Benzyl 1-benzylpiperazine-2-carboxylate (CAS 1253226-48-0)
- 9-Ethyl-7-methoxy-1,3-dihydrofuro[3,4-b]quinoline (CAS 540804-03-3)
- DAPK Substrate Peptide (CAS 386769-53-5)
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