4-(4-Fluorophenyl)-N-(p-tolyl)piperazine-1-carboxamide CAS 710312-06-4

Purity 97%+In StockPharmaceutical Standards
CAS No.710312-06-4
Molecular FormulaC18H20FN3O
Molecular Weight313.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(4-Fluorophenyl)-N-(p-tolyl)piperazine-1-carboxamide CAS 710312-06-4 chemical structure

Description

The occurrence of 4-(4-Fluorophenyl)-N-(p-tolyl)piperazine-1-carboxamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-(4-Fluorophenyl)-N-(p-tolyl)piperazine-1-carboxamide (CAS 710312-06-4), molecular formula C18H20FN3O and molecular weight 313.37 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-(4-Fluorophenyl)-N-(p-tolyl)piperazine-1-carboxamide (C18H20FN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-(4-Fluorophenyl)-N-(p-tolyl)piperazine-1-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H20FN3O
Molecular Weight313.37 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF-containing
Nitrogen Atoms3

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