2-(6-Phenyl-4-(trifluoromethyl)pyridin-2-yl)phenol CAS 710354-96-4
| CAS No. | 710354-96-4 |
| Molecular Formula | C18H12F3NO |
| Molecular Weight | 315.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(6-Phenyl-4-(trifluoromethyl)pyridin-2-yl)phenol (CAS 710354-96-4), a certified reference material (molecular formula C18H12F3NO, MW 315.29 g/mol) for analytical method development and quality control.
The molecular framework of 2-(6-Phenyl-4-(trifluoromethyl)pyridin-2-yl)phenol (C18H12F3NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-(6-Phenyl-4-(trifluoromethyl)pyridin-2-yl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H12F3NO |
| Molecular Weight | 315.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Phenyl Standards
- N'-[6-(Trifluoromethyl)pyridine-3-carbonyl]cyclohexanecarbohydrazide (CAS 1092346-05-8)
- 2-((3-(Trifluoromethyl)phenyl)carbamoyl)cyclohexane-1-carboxylic acid (CAS 304674-19-9)
- 1-[5-(1-{[3-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethyl)-1H-pyrazol-1-yl]ethan-1-one (CAS 1210834-67-5)
- (4-((3-(Trifluoromethyl)phenyl)sulfonyl)phenyl)methanamine (CAS 1374864-79-5)
- Ethyl 2-(2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)acetate (CAS 680215-92-3)
- Ethyl 2-{2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}acetate (CAS 78743-00-7)
- N-(4-(Trifluoromethyl)benzyl)benzenesulfonamide (CAS 874813-22-6)
- 3-[3-(Trifluoromethyl)benzamido]thiophene-2-carboxylic acid (CAS 866150-49-4)
Recommended Standards
- 2-(Quinolin-2-yl)-1-(3-(trifluoromethyl)phenyl)ethan-1-one (CAS 849021-38-1)
- 1-[4-cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-4-carboxylic acid (CAS 862652-23-1)
- 2-(Quinolin-2-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one (CAS 283597-72-8)
- 1,1,1-TRifluoro-4-(2-phenyl-1h-indol-3-yl)but-3-en-2-one (CAS 202074-32-6)
- 4-(2-Methylsulfanyl-pyrimidin-4-ylamino)-cyclohexanol (CAS 1289386-14-6)
- (S,S,S)-AHPC ·xHCl (CAS 2115897-23-7)
- 2-[(2-methylthieno[2,3-e][1,3]benzothiazol-5-yl)oxy]ethanamine dihydrochloride (CAS 1171669-99-0)
- 4-Bromo-6-(difluoromethyl)-3-hydroxy-2-nitropyridine (CAS 1806072-86-5)
- 3-(3,5-Dichlorophenoxy)azetidine (CAS 1339830-61-3)
- Dolutegravir Impurity 49 (CAS CATO-C4X-162049)
- 6-Chloro-N-(3-(trifluoromethyl)phenyl)nicotinamide (CAS 384847-78-3)
- N-(5-(Cyclopropylsulfonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)acetamide (CAS 1448052-39-8)
- 1-(1,1-Difluoropropyl)-4-(trifluoromethyl)benzene (CAS 1138445-54-1)
- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
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