8-Fluoroquinoline-3-carbonitrile CAS 71083-52-8
| CAS No. | 71083-52-8 |
| Molecular Formula | C10H5FN2 |
| Molecular Weight | 172.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 8-Fluoroquinoline-3-carbonitrile (CAS 71083-52-8), a certified reference material (molecular formula C10H5FN2, MW 172.16 g/mol) for analytical method development and quality control.
Structurally, 8-Fluoroquinoline-3-carbonitrile (C10H5FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 172.16 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H5FN2 |
| Molecular Weight | 172.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoroquinoline Standards
- 6-Fluoroquinoline-4-carbonitrile (CAS 1001906-58-6)
- 6-Fluoroquinoline-8-carbonitrile (CAS 1368394-42-6)
- 7-Fluoroquinoline-8-carbonitrile (CAS 1529615-11-9)
- 5-Fluoroquinoline-8-carbonitrile (CAS 1823944-97-3)
- 2-Fluoroquinoline-4-carbonitrile (CAS 50504-19-3)
- 3-Fluoroquinoline-6-carbonitrile (CAS 2177258-32-9)
- 3-Fluoroquinoline-8-carbonitrile (CAS 2177264-04-7)
- 5-Fluoroquinoline-3-carbonitrile (CAS 2102412-57-5)
Recommended Standards
- 7-Fluoroquinoline-6-carbonitrile (CAS 956901-17-0)
- 8-Fluoroquinoline-4-carbonitrile (CAS 949535-30-2)
- 7-Fluoroquinoline-3-carbonitrile (CAS 352521-51-8)
- 8-Fluoroquinoline-5-carbonitrile (CAS 2092000-25-2)
- (Z)-Octadec-7-enoic acid (CAS 13126-31-3)
- 4-Ethoxy-6-(2-fluoroethoxy)pyrimidin-5-amine (CAS 326832-16-0)
- 3-Hydroxyquinoxaline-2-carbaldehyde (CAS 49568-65-2)
- 1,1-Dimethylethyl 6-fluoro-7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylate (CAS 2875088-09-6)
- Ertugliflozin Impurity 54 (CAS 1528636-29-4)
- 4-((4-(Ethyl(isopropyl)amino)phenyl)imino)-N-methyl-1-oxo-1,4-dihydronaphthalene-2-carboxamide (CAS 161358-44-7)
- 7-Cyclopropylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 832114-69-9)
- Ezetimibe Impurity 133 (CAS CATO-C4X-1098133)
- 1-(Furan-2-ylmethyl)pyrrolidine-3-carboxylic acid (CAS 1340256-81-6)
- Fibrinogen Related Peptide (CAS 80755-86-8)
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