N-(1H-indol-5-yl)thiophene-2-sulfonamide CAS 710945-69-0
| CAS No. | 710945-69-0 |
| Molecular Formula | C12H10N2O2S2 |
| Molecular Weight | 278.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, N-(1H-indol-5-yl)thiophene-2-sulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 278.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
N-(1H-indol-5-yl)thiophene-2-sulfonamide (CAS 710945-69-0), molecular formula C12H10N2O2S2 and molecular weight 278.35 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10N2O2S2 |
| Molecular Weight | 278.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Recommended Standards
- N-(1-(1H-Benzo[d][1,2,3]triazol-1-yl)-2-methylprop-1-en-1-yl)-N-methylaniline (CAS 305861-35-2)
- n-(2-(1h-Indol-3-yl)ethyl)-3-methylbenzamide (CAS 881487-84-9)
- N-((1-Ethylpyrrolidin-2-yl)methyl)-4-methoxy-2-methylpyrimidine-5-carboxamide (CAS 72412-52-3)
- n-(2-(1h-Indol-3-yl)ethyl)-n-(p-tolyl)formamide (CAS 881597-49-5)
- Ethanol, 2-phenoxy-, phosphate, potassium salt (CAS 68511-20-6)
- 3,5-Difluoro-4-phenyl-4H-1,2,4-triazole (CAS 955050-68-7)
- (3S)-2-(tert-Butoxycarbonyl)-5,5-difluoro-2-azabicyclo[2.2.2]octane-3-carboxylic acid (CAS 1272757-15-9)
- Iohexol Impurity 48 (CAS 2992672-98-5)
- 2-[3-(aminomethyl)piperidin-1-yl]acetonitrile dihydrochloride (CAS 1354951-26-0)
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- 4-Isopropylcyclohexane-1-carboximidamide (CAS 1394116-65-4)
- 9-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)nonanoic acid (CAS 212688-52-3)
- 3-[Bis(4-fluorophenyl)methyl]-4-hydroxypent-3-en-2-one (CAS 53135-11-8)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
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