Cefoperazone EP Impurity B CAS 711598-76-4
| CAS No. | 711598-76-4 |
| Molecular Formula | C25H27N9O8S2 |
| Molecular Weight | 645.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cefoperazone EP Impurity B is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Cefoperazone EP Impurity B (CAS 711598-76-4), a pharmacopoeial impurity reference standard (molecular formula C25H27N9O8S2, MW 645.67 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Cefoperazone EP Impurity B (C25H27N9O8S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cefoperazone EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H27N9O8S2 |
| Molecular Weight | 645.67 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 9 |
| Sulfur Atoms | 2 |
Related Cefoperazone Standards
- Cefoperazone Impurity 13 (CAS CATO-C4X-114913)
- Cefoperazone Impurity 25 (CAS CATO-C4X-114925)
- Cefoperazone Impurity 33 (CAS CATO-C4X-114933)
- Cefoperazone (CAS 62893-19-0)
- Cefoperazone EP Impurity F (CAS 1315481-36-7)
- Cefoperazone Impurity N11 (CAS 68779-10-2)
- Cefoperazone Impurity N12 (CAS 711590-76-4)
- Cefoperazone-d5 (CAS 2410425-70-4)
Recommended Standards
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- Carprofen EP Impurity B (CAS 52263-68-0)
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