3-Formyl-4-hydroxy-5-methoxybenzoic acid CAS 712-53-8
| CAS No. | 712-53-8 |
| Molecular Formula | C9H8O5 |
| Molecular Weight | 196.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Formyl-4-hydroxy-5-methoxybenzoic acid (CAS 712-53-8), molecular formula C9H8O5 and molecular weight 196.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Formyl-4-hydroxy-5-methoxybenzoic acid (C9H8O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H8O5 |
| Molecular Weight | 196.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Formyl Standards
- Methyl 2-formyl-3,5-dihydroxybenzoate (CAS 16849-78-8)
- 2-Formyl-4-hydroxy-5-methoxybenzoic acid (CAS 1895397-08-6)
- 6-Formyl-2-hydroxy-3-methoxybenzoic acid (CAS 4743-49-1)
- 6-Formyl-4-nitropicolinic acid (CAS 1289010-97-4)
- 2-Formyl-6-nitroisonicotinic acid (CAS 1289172-34-4)
- 2-(3-Formyl-1H-pyrrol-1-yl)benzonitrile (CAS 156496-63-8)
- ethyl 4-formyl-1,3-dimethyl-1H-pyrazole-5-carboxylate (CAS 166313-50-4)
- 4-(2-Formyl-1h-pyrrol-1-yl)benzonitrile (CAS 169036-66-2)
Recommended Standards
- 3-Amino-5-nitrobenzohydrazide (CAS 205652-98-8)
- 3-Hydroxy-4-(methoxycarbonyl)benzoic acid (CAS 808123-00-4)
- 3-Amino-5,7-dimethylisoxazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione (CAS 78932-78-2)
- 3-Methoxy-2-nitrobenzamide (CAS 99595-85-4)
- n-(2-Cyanoethyl)-n-methylformamide (CAS 54014-00-5)
- N-(Pyrimidin-4-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1419221-36-5)
- 3-(Dimethoxy)-5-(tributylstannyl)pyridine (CAS 1264193-67-0)
- Ethyl 1-((2-benzamidoethyl)sulfonyl)piperidine-4-carboxylate (CAS 899758-54-4)
- 1-(2-ethyl-1,3-thiazol-4-yl)methanamine (CAS 933707-20-1)
- N-(2,2,2-trifluoroethyl)tetrahydro-2H-pyran-4-amine hydrochloride (CAS 1949816-07-2)
- 6709-58-6 TR-022590 fast dark blue r salt,azoic diazo no.51,diazo fast dark blue r,4-amino-2,5-dimethoxy-4'-nitroazodichlorobenzene diazonium salt,c.i.37195 (CAS 6709-58-6)
- 1,2,3,6-Tetrahydropyridine-2-carbonitrile (CAS 87780-70-9)
- 11-Acetateundecyltrimethoxysilane (CAS 1197981-12-6)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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