N-(2,6-Dimethylpyrimidin-4-yl)-3-fluorobenzamide CAS 712309-05-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2,6-Dimethylpyrimidin-4-yl)-3-fluorobenzamide.

N-(2,6-Dimethylpyrimidin-4-yl)-3-fluorobenzamide (CAS 712309-05-2), molecular formula C13H12FN3O and molecular weight 245.25 g/mol, is a CATO reference standard with documented purity and traceability.

N-(2,6-Dimethylpyrimidin-4-yl)-3-fluorobenzamide (C13H12FN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(2,6-Dimethylpyrimidin-4-yl)-3-fluorobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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