4-(4-Bromo-2-chlorophenoxy)aniline CAS 71258-04-3
| CAS No. | 71258-04-3 |
| Molecular Formula | C12H9BrClNO |
| Molecular Weight | 298.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Bromo-2-chlorophenoxy)aniline.
4-(4-Bromo-2-chlorophenoxy)aniline (CAS 71258-04-3) is a high-purity analytical reference standard with the molecular formula C12H9BrClNO and a molecular weight of 298.56 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, 4-(4-Bromo-2-chlorophenoxy)aniline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 298.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(4-Bromo-2-chlorophenoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9BrClNO |
| Molecular Weight | 298.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-4-(4-chlorophenoxy)aniline (CAS 1092306-74-5)
- 2-bromo-5-[(3-chlorophenyl)methoxy]pyridine (CAS 1121634-68-1)
- 3-(5-Bromo-2-chlorophenoxy)methylpyridine (CAS 1291487-23-4)
- N-(4-bromo-2-chloronaphthalen-1-yl)acetamide (CAS 13711-36-9)
- methyl 7-bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine-5-carboxylate (CAS 1416438-04-4)
- 4-Bromo-2-(3-chlorophenoxy)-phenylamine (CAS 1485735-15-6)
- 5-Bromo-2-(4-chlorophenoxy)aniline (CAS 15212-00-7)
- 5-Bromo-2-(2-chlorophenoxy)aniline (CAS 56966-50-8)
Recommended Standards
- 4-(2-Bromophenoxy)-3-chloroaniline (CAS 945006-23-5)
- 5-(Benzyloxy)-3-bromo-2-chloropyridine (CAS 864775-95-1)
- 3-(Benzyloxy)-5-bromo-2-chloropyridine (CAS 891785-18-5)
- 5,6-Dichloro-2-(2-chloropyridin-3-yl)-1H-benzo[d]imidazole (CAS 337920-55-5)
- 1-ethyl-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate (CAS 1628604-71-6)
- 3-Azabicyclo[3.3.1]nonane (CAS 280-70-6)
- rac-8,14-Bis(tert-butyldimethylsilyloxy) Efavirenz-d4 (CAS 1329840-70-1)
- 3,5-Dibromo-2,4-dimethoxypyridine (CAS 443770-52-3)
- N-Fmoc-(S)-2,6-difluoro-α-methylphenylalanine (CAS 1223105-51-8)
- 3-Chloro-1H-pyrazol-4-amine (CAS 103286-54-0)
- 1-(Bromomethyl)-2-((phenylsulfonyl)methyl)benzene (CAS 88116-02-3)
- Methyl 4-[2-amino-4-(piperidine-1-sulfonyl)phenoxy]benzoate (CAS 735322-72-2)
- 1-(4-Fluorobenzyl)-1h-imidazole-5-carboxylic acid (CAS 1439902-43-8)
- ([D?]Val?·1?)-C-Peptide (human) (CAS 1802078-41-6)
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