N-Methylnaphthalene-2-sulfonamide CAS 7147-68-4
| CAS No. | 7147-68-4 |
| Molecular Formula | C11H11NO2S |
| Molecular Weight | 221.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N-Methylnaphthalene-2-sulfonamide (CAS 7147-68-4) is a high-purity analytical reference standard with the molecular formula C11H11NO2S and a molecular weight of 221.28 g/mol.
The molecular framework of N-Methylnaphthalene-2-sulfonamide (C11H11NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11NO2S |
| Molecular Weight | 221.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related N Standards
- 4-Methylnaphthalene-1-sulfonamide (CAS 10447-10-6)
- 2-Methylnaphthalene-1-sulfonamide (CAS 859071-90-2)
- 6-methylnaphthalene-2-sulfonamide (CAS 215958-81-9)
- methyl 6-methylnaphthalene-1-carboxylate (CAS 91902-60-2)
- 1-Benzyl-3-methylnaphthalene (CAS 93870-53-2)
- 4-Methylnaphthalene-1-carbonyl chloride (CAS 87700-67-2)
- 4-Methylnaphthalene-1-sulfonyl chloride (CAS 10447-11-7)
- 6-Methylnaphthalene-2-sulfonyl chloride (CAS 1875-72-5)
Recommended Standards
- N-Methoxy-N-methylbenzo[b]thiophene-2-carboxamide (CAS 279226-22-1)
- Pyrrothiogatain (CAS 477888-48-5)
- N-Cyano-N'-(4-methoxyphenyl)-S-methylisothiourea (CAS 75565-12-7)
- 60858-95-9 Diazald-N-methyl-13C N-Methyl-13C-N-nitroso-p-toluenesulfonamide (CAS 60858-95-9)
- Methyl 3-amino-4-(2,2-difluoroethoxy)benzoate (CAS 1184079-17-1)
- 1-(Trifluoromethoxy)-3-(trifluoromethyl)benzene (CAS 42908-82-7)
- Bis(3-bromo-1,2,4-thiadiazol-5-ylsulfinyl)methane (CAS 845879-07-4)
- Methyl 2-bromo-2-(4-bromophenyl)acetate (CAS 60079-77-8)
- (3,4,5-Trimethoxy-2-nitrophenyl)methanol (CAS 5435-28-9)
- 4,5-Dimethyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate (CAS 458566-99-9)
- 9-Benzyl-9-azabicyclo[3.3.1]nonan-3-one hydrochloride (CAS 2291-59-0)
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