4-(4-Nitrobenzylidene)-2-phenyloxazol-5(4H)-one CAS 7152-75-2
| CAS No. | 7152-75-2 |
| Molecular Formula | C16H10N2O4 |
| Molecular Weight | 294.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(4-Nitrobenzylidene)-2-phenyloxazol-5(4H)-one.
4-(4-Nitrobenzylidene)-2-phenyloxazol-5(4H)-one (CAS 7152-75-2), molecular formula C16H10N2O4 and molecular weight 294.26 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-Nitrobenzylidene)-2-phenyloxazol-5(4H)-one (C16H10N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Nitrobenzylidene)-2-phenyloxazol-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10N2O4 |
| Molecular Weight | 294.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 2 |
Related Nitrobenzylidene Standards
- (Z)-4-(2-nitrobenzylidene)-2-phenyloxazol-5(4h)-one (CAS 66949-10-8)
- (Z)-4-(3-Nitrobenzylidene)-2-phenyloxazol-5(4H)-one (CAS 66949-11-9)
- (Z)-4-(4-nitrobenzylidene)-2-phenyloxazol-5(4h)-one (CAS 57427-80-2)
- (Z)-4-(4-Nitrobenzylidene)-3-phenylisoxazol-5(4H)-one (CAS 61588-01-0)
- 3-((2-Nitrobenzylidene)amino)quinazolin-4(3H)-one (CAS 88404-50-6)
- 3-((4-Nitrobenzylidene)amino)quinazolin-4(3H)-one (CAS 62176-69-6)
- (E)-2-((4-nitrobenzylidene)amino)isoindoline-1,3-dione (CAS 32387-08-9)
- (p-Nitrobenzylidene)malonic Acid Diethyl Ester (CAS 22399-00-4)
Recommended Standards
- 4-(4-Formylpyrimidin-2-yl)phenyl furan-2-carboxylate (CAS 477870-58-9)
- 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 3-[3-(benzoyloxy)-1-propyn-1-yl]-1,5-dihydro- (CAS 2591494-65-2)
- 3-O-Levulinoyl-3,5-dihydroxy Benzoic Acid Acetate (CAS 861446-21-1)
- 4-Nitro-2-(4-vinylphenyl)isoindoline-1,3-dione (CAS 89014-95-9)
- 1-((1-(Pyrazin-2-yl)piperidin-4-yl)methyl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 1396801-61-8)
- Methyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5-dimethylthiophene-3-carboxylate (CAS 300812-61-7)
- 2,2,2-Trifluoro-N-(2-nitrophenyl)acetamide (CAS 2727-72-2)
- 2,5-Divinylbenzene-1,4-diamine (CAS 1631999-89-7)
- 2-Chloro-N-((6-methoxypyridazin-3-yl)methyl)-N-methylacetamide (CAS 1353967-01-7)
- 2-Amino-6,7-dihydrobenzo[d]thiazol-5(4H)-one (CAS 1934503-99-7)
- 6-Amino-5-((3-chlorophenyl)amino)-7-((4-chlorophenyl)sulfonyl)-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile (CAS 691396-67-5)
- Amido Ethyl Meloxicam (Meloxicam Impurity) (CAS 881399-30-0)
- 4-(Pyridin-3-yl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine (CAS 1255099-15-0)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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