4-Chloro-2-nitrophenylurea CAS 7153-86-8
| CAS No. | 7153-86-8 |
| Molecular Formula | C7H6ClN3O3 |
| Molecular Weight | 215.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-2-nitrophenylurea (CAS 7153-86-8), molecular formula C7H6ClN3O3 and molecular weight 215.59 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Chloro-2-nitrophenylurea (C7H6ClN3O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 215.59 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3O3 |
| Molecular Weight | 215.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-4-methyl-5-nitrobenzoic acid (CAS 101580-96-5)
- 2-Chloro-N-(3-nitropyridin-2-yl)acetamide (CAS 1065483-83-1)
- 6-Chloro-4-(methoxycarbonyl)picolinic acid (CAS 1206249-69-5)
- 2-Chloro-6-(methoxycarbonyl)isonicotinic acid (CAS 1206250-39-6)
- 3-Chloro-2-methyl-5-nitrobenzoic acid (CAS 1227268-71-4)
- 7-Chloro-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine-8-carboxylic acid (CAS 1305325-09-0)
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Recommended Standards
- 4-Chloro-2-methyl-5-nitrobenzoic acid (CAS 476660-41-0)
- 4-Chloro-3-nitrobenzhydrazide (CAS 77938-04-6)
- 4-Chloro-2-methyl-3-nitrobenzoic acid (CAS 950915-10-3)
- 4-Chloro-3-nitrophenylacetic acid (CAS 37777-68-7)
- 2-Bromo-1-naphthonitrile (CAS 138887-02-2)
- 3,4-Dimethyl-N-(quinolin-2-ylmethylene)aniline (CAS 88346-85-4)
- 1-[(3-ethyl-1,2,4-oxadiazol-5-yl)methyl]piperidin-3-ol (CAS 1250111-68-2)
- 4-(Benzyloxy)-2-bromo-5-methoxybenzoic acid (CAS 214848-02-9)
- Dipropyl succinate (CAS 925-15-5)
- 5-Amino-2-methylpyridine-3-boronic Acid Pinacol Ester (CAS 1800401-67-5)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-(trifluoromethoxy)phenyl)urea (CAS 1024431-81-9)
- 3-Bromo-5-(4-thiomorpholinylsulfonyl)benzoic acid (CAS 522652-13-7)
- 2137AF 4-(4-Methyl-piperazin-1-yl)-pentanoic acid 889939-93-9 C10H20N2O2 (CAS 889939-93-9)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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