4-Bromo-3-(N-methylsulfamoyl)benzoic acid CAS 716358-64-4
| CAS No. | 716358-64-4 |
| Molecular Formula | C8H8BrNO4S |
| Molecular Weight | 294.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Bromo-3-(N-methylsulfamoyl)benzoic acid (CAS 716358-64-4), a certified reference material (molecular formula C8H8BrNO4S, MW 294.12 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution, 4-Bromo-3-(N-methylsulfamoyl)benzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8BrNO4S |
| Molecular Weight | 294.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 5-BRomo-2-fluoro-n-phenylbenzamide (CAS 1016847-17-8)
- Methyl 4-bromo-2-sulfamoylbenzoate (CAS 1202366-59-3)
- 5-Bromo-2-(methylsulfonamido)benzoic Acid (CAS 1225713-29-0)
- 7-Bromo-2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamide (CAS 1342745-35-0)
- Methyl 3-bromo-5-sulfamoylbenzoate (CAS 1343983-13-0)
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- 5-Bromo-2-methyl-3-sulfamoylbenzoic acid (CAS 1375472-31-3)
- 3-Bromo-2-methyl-5-sulfamoylbenzoic acid (CAS 1489091-39-5)
Recommended Standards
- 4-Bromo-2-methoxycarbonylbenzenesulfonamide (CAS 953742-67-1)
- 4-Bromo-N-(2-fluorophenyl)benzamide (CAS 325471-58-7)
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- 4-Bromo-N-(3-fluorophenyl)benzamide (CAS 306745-79-9)
- 1-(tert-Butyl)-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 116162-74-4)
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- Acetophenone-DNPH (CAS 1677-87-8)
- 3-Phenyl-4-piperidinol (CAS 874361-13-4)
- 1-Methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptan-2-yl N-[(4-cyanophenyl)methyl]-N-(4-methylbenzenesulfonyl)carbamate (CAS 1005096-41-2)
- 4-(4-Bromobutyl)oxane (CAS 1050496-76-8)
- 7-(((3R,4R)-3-Hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl)methyl)-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one (CAS 548486-59-5)
- 1-Amino-5-bromouracil (CAS 127984-93-4)
- 1-(Pyridin-2-ylmethyl)-4-(trifluoromethyl)-1h-pyrrole-3-carboxylic acid (CAS 1221724-75-9)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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