2-Chloro-4-{[(trifluoromethyl)sulfonyl]amino}benzoic acid CAS 716361-56-7
| CAS No. | 716361-56-7 |
| Molecular Formula | C8H5ClF3NO4S |
| Molecular Weight | 303.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Chloro-4-{[(trifluoromethyl)sulfonyl]amino}benzoic acid (CAS 716361-56-7) is a high-purity analytical reference standard with the molecular formula C8H5ClF3NO4S and a molecular weight of 303.64 g/mol.
The molecular framework of 2-Chloro-4-{[(trifluoromethyl)sulfonyl]amino}benzoic acid (C8H5ClF3NO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF3NO4S |
| Molecular Weight | 303.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 1-(Benzo[d][1,3]dioxol-5-yl)-N-phenylmethanimine (CAS 853099-64-6)
- 2-(6-Bromopyridin-2-yloxy)acetonitrile (CAS 545426-95-7)
- 3-(Hydroxymethyl)phenethyl furan-3-carboxylate (CAS 61761-78-2)
- N-(4-chlorophenyl)-2-(pyridin-4-yl)thiazole-4-carboxamide (CAS 286860-10-4)
- [1-(Methoxymethyl)cyclobutyl]methanesulfonyl chloride (CAS 1850318-98-7)
- (Z,Z)-1,3-Diiminoisoindoline (CAS 160956-25-2)
- 9-Bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-amine (CAS 886367-32-4)
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(naphthalen-2-ylmethyl)propanoic acid (CAS 1260613-63-5)
- 1-Methyl-2-nitro-1H-pyrrole (CAS 823-37-0)
- Tirzepatide Impurity 26 X TFA Salt (CAS CATO-C4X-324026)
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