2-Hydroxy-N-(p-tolyl)benzamide CAS 7164-80-9

Purity 97%+In StockPharmaceutical Standards
CAS No.7164-80-9
Molecular FormulaC14H13NO2
Molecular Weight227.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Hydroxy-N-(p-tolyl)benzamide CAS 7164-80-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 227.26 g/mol gives 2-Hydroxy-N-(p-tolyl)benzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Hydroxy-N-(p-tolyl)benzamide (CAS 7164-80-9) is a high-purity analytical reference standard with the molecular formula C14H13NO2 and a molecular weight of 227.26 g/mol.

2-Hydroxy-N-(p-tolyl)benzamide (C14H13NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Hydroxy-N-(p-tolyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H13NO2
Molecular Weight227.26 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1959
Nitrogen Atoms1

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