5-Acetyl-3-phenyl-1,3,4-thiadiazol-2(3H)-one CAS 71687-17-7
| CAS No. | 71687-17-7 |
| Molecular Formula | C10H8N2O2S |
| Molecular Weight | 220.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Acetyl-3-phenyl-1,3,4-thiadiazol-2(3H)-one.
5-Acetyl-3-phenyl-1,3,4-thiadiazol-2(3H)-one (CAS 71687-17-7) is a high-purity analytical reference standard with the molecular formula C10H8N2O2S and a molecular weight of 220.25 g/mol.
The molecular framework of 5-Acetyl-3-phenyl-1,3,4-thiadiazol-2(3H)-one (C10H8N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Acetyl-3-phenyl-1,3,4-thiadiazol-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2S |
| Molecular Weight | 220.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- 5-[(3-Hydroxyphenyl)methylene]-2-thioxo-4-imidazolidinone (CAS 74920-46-0)
- 5-Amino-2-phenyl-1,3-thiazole-4-carboxylic acid (CAS 923010-77-9)
- 5-(Phenylamino)-1,3-thiazole-4-carboxylic acid (CAS 84636-43-1)
- 5-Methyl-2-(pyridin-3-yl)thiazole-4-carboxylic acid (CAS 334017-42-4)
- 2-chloro-N-(4-chlorobenzyl)propanamide (CAS 90919-81-6)
- 2-Acetamido-5-bromoisonicotinic Acid (CAS 871269-03-3)
- 1-bromoisooctane (CAS 65871-38-7)
- 1-((5-Chloro-3-methylbenzo[b]thiophen-2-yl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 861207-40-1)
- Methyl 4,5-dimethoxy-2-(methylamino)benzoate (CAS 350228-61-4)
- 4-(Cyclohexyl(methyl)amino)-3-nitrobenzoic acid (CAS 309943-04-2)
- 3-Amino-1-((5-chlorothiophen-2-yl)methyl)pyridin-2(1h)-one (CAS 1248242-42-3)
- (7-Chloro-2-methyl-1H-indol-3-yl)-acetic acid (CAS 25177-74-6)
- 3-Bromo-1-(difluoromethyl)-4-iodo-1H-pyrazole (CAS 2739868-05-2)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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