Pyrrolidine-2,5-dicarboxylic acid CAS 72000-65-8
| CAS No. | 72000-65-8 |
| Molecular Formula | C6H9NO4 |
| Molecular Weight | 159.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Pyrrolidine-2,5-dicarboxylic acid (CAS 72000-65-8) is a high-purity analytical reference standard with the molecular formula C6H9NO4 and a molecular weight of 159.14 g/mol.
The molecular framework of Pyrrolidine-2,5-dicarboxylic acid (C6H9NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9NO4 |
| Molecular Weight | 159.14 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1977 |
| Nitrogen Atoms | 1 |
Related Pyrrolidine Standards
- Pyrrolidine-3,4-dicarboxylic acid (CAS 159694-26-5)
- (S)-Pyrrolidine-1,2-dicarboxylic acid (CAS 54399-67-6)
- Pyrrolidine-1,2-dicarboxylic acid (CAS 5626-63-1)
- Pyrrolidine-2,4-dicarboxylic acid (CAS 99319-03-6)
- Propyl pyrrolidine-1-carboxylate (CAS 500299-62-7)
- Pyrrolidine-1-butyric acid (CAS 85614-44-4)
- Pyrrolidine-2,5-dicarboxamide (CAS 484664-62-2)
- pyrrolidine-3,4-dicarboxamide (CAS 1989671-65-9)
Recommended Standards
- Quinoline-5,6-dione (CAS 7467-33-6)
- Oxiracetam Impurity 1 (CAS 77191-37-8)
- Pyrido[2,3-b]pyrazine-8-carbaldehyde (CAS 933716-73-5)
- Cefodizime Impurity 10 (CAS 66508-93-8)
- tert-Butyl 4-(4-amino-3-fluorophenyl)piperidine-1-carboxylate (CAS 1488342-80-8)
- (S)-4-Amino-2-(carboxyformamido)butanoic acid (CAS 151842-77-2)
- 6-Cyclopropyl-2-imino-2,3-dihydropyrimidin-4(1h)-one (CAS 21573-08-0)
- 2-(3-Bromonaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1595078-11-7)
- 2-[4-(cyanomethoxy)phenyl]acetic acid (CAS 1019446-81-1)
- 1,3,4-Trimethylcyclohex-3-en-1-amine hydrochloride (CAS 2137780-79-9)
- (S)-2-(2-(2-(3-(Furan-2-yl)acrylamido)acetamido)-4-methylpentanamido)acetic acid (CAS 56186-48-2)
- 1-Cyclopropyl-7-(2,6-Dimethylpyridin-4-yl-6,8-Difluoro-4-Oxoquinoline-3-Carboxylic Acid (CAS 123942-05-2)
- 1-Deoxy-1-nitro-D-mannitol (CAS 14199-83-8)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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