2-[3-(Trifluoromethyl)phenyl]cyclopropane-1-carboxylic acid CAS 721-22-2

Purity 97%+In StockPharmaceutical Standards
CAS No.721-22-2
Molecular FormulaC11H9F3O2
Molecular Weight230.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[3-(Trifluoromethyl)phenyl]cyclopropane-1-carboxylic acid CAS 721-22-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[3-(Trifluoromethyl)phenyl]cyclopropane-1-carboxylic acid.

CATO supplies 2-[3-(Trifluoromethyl)phenyl]cyclopropane-1-carboxylic acid (CAS 721-22-2), a certified reference material (molecular formula C11H9F3O2, MW 230.18 g/mol) for analytical method development and quality control.

Structurally, 2-[3-(Trifluoromethyl)phenyl]cyclopropane-1-carboxylic acid (C11H9F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 230.18 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H9F3O2
Molecular Weight230.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing

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