Alfuzosin EP Impurity C HCl CAS 72104-34-8
| CAS No. | 72104-34-8 |
| Molecular Formula | C19H27N5O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Alfuzosin EP Impurity C HCl (CAS 72104-34-8) is a certified pharmaceutical impurity reference standard with the molecular formula C19H27N5O4HCl and a molecular weight of 425.91 g/mol.
Structurally, Alfuzosin EP Impurity C HCl (C19H27N5O4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 425.91 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H27N5O4 HCl |
| Molecular Weight | 425.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Alfuzosin Standards
- Alfuzosin-d (CAS 1006717-24-3)
- Alfuzosin-D6 (CAS 1006717-31-2)
- Alfuzosin EP Impurity E (CAS 1026411-59-5)
- Alfuzosin-d3 Hydrochloride (CAS 1216383-97-9)
- (±)-Alfuzosin D7 Hydrochloride (CAS 1276197-14-8)
- Alfuzosin EP Impurity B Hydrochloride (CAS 132900-51-7)
- Alfuzosin-d7 (CAS 1346746-88-0)
- Alfuzosin EP Impurity E HCl (CAS 1796934-51-4)
Recommended Standards
- Rasagiline Impurity 19 (CAS CATO-C4X-191319)
- Naltrexone impurity 31 (CAS 20410-98-4)
- Neostigmine Impurity N1 (CAS 2434689-89-9)
- 1-(3-chloro-4-methoxy-phenyl)hexahydropyrimidine-2,4-dione (CAS 1062554-70-4)
- 2-(2-(4,5-Dichloro-1H-imidazol-1-yl)acetyl)-N-methylhydrazine-1-carbothioamide (CAS 650615-65-9)
- 2-Amino-N-(p-tolyl)-3a,4,5,6,7,7a-hexahydrobenzo[b]thiophene-3-carboxamide (CAS 1210816-27-5)
- 2,5-Dichloro-3-(chloromethyl)-8-methylquinoline (CAS 948292-13-5)
- 2,3-Difluorobenzotrifluoride (CAS 64248-59-5)
- 1-(2-Fluorobenzyl)-3-(piperazin-1-yl)pyrazin-2(1H)-one (CAS 1708288-83-8)
- TAT 14 Peptide (Nrf2 Activator III) (CAS 1362661-34-4)
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