3-[(2-bromo-5-methylphenyl)sulfamoyl]benzoic acid CAS 721418-18-4
| CAS No. | 721418-18-4 |
| Molecular Formula | C14H12BrNO4S |
| Molecular Weight | 370.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-[(2-bromo-5-methylphenyl)sulfamoyl]benzoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-[(2-bromo-5-methylphenyl)sulfamoyl]benzoic acid (CAS 721418-18-4), molecular formula C14H12BrNO4S and molecular weight 370.22 g/mol, is a CATO reference standard with documented purity and traceability.
3-[(2-bromo-5-methylphenyl)sulfamoyl]benzoic acid (C14H12BrNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-[(2-bromo-5-methylphenyl)sulfamoyl]benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12BrNO4S |
| Molecular Weight | 370.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related bromo Standards
- 4-Bromo-3-[methyl(phenyl)sulfamoyl]benzoic acid (CAS 941196-03-8)
- 4-Bromo-N-[4-(hydrazinecarbonyl)phenyl]benzene-1-sulfonamide (CAS 59256-25-6)
- Methyl 5-bromo-2-methoxy-4-(thiophene-2-carboxamido)benzoate (CAS 477871-60-6)
- 3-Bromo-8-methoxy-6,6-dimethyl-5H-benzo[b]carbazol-11(6H)-one (CAS 1256576-68-7)
- 1-Bromo-8-methoxy-6,6-dimethyl-5H-benzo[b]carbazol-11(6H)-one (CAS 1332605-45-4)
- Bromo-PEG5-azide (CAS 1402411-90-8)
- 2-Bromo-5-ethoxy-4-(2-oxo-2-(piperidin-1-yl)ethoxy)benzaldehyde (CAS 1427023-31-1)
- 2-Bromo-N-cyclopropyl-N-(imidazo[1,2-a]pyridin-3-ylmethyl)benzamide (CAS 1448136-56-8)
Recommended Standards
- 3-(3-((4-Bromobenzyl)thio)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propanoic acid (CAS 898607-83-5)
- 3-[(Benzylamino)sulfonyl]-4-bromobenzoic acid (CAS 312758-94-4)
- 2-(7-Fluoro-3-(methoxymethoxy)-8-(prop-1-yn-1-yl)naphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2763159-16-4)
- (E)-N'-(2,2,3,3,3-Pentafluoropropylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2236129-83-0)
- 4,4'-(1-Benzyl-1H-1,2,4-triazole-3,5-diyl)dipyridine (CAS 55391-37-2)
- 3-(Benzo[d][1,3]dioxol-5-yl)propan-1-ol (CAS 7031-03-0)
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- N-(4-Chlorophenyl)-2-(3,4-dichloro-1-methyl-1H-pyrazol-5-yl)-2-methyl-1-hydrazinecarboxamide (CAS 318284-27-4)
- N-(3-Amino-2-methylphenyl)-2-[4-(tert-butyl)-phenoxy]acetamide (CAS 1020056-46-5)
- 2,2-Dimethyl-5-(2-phenyl-2-adamantyl)-1,3-dioxane-4,6-dione (CAS 133709-17-8)
- Dexamethasone dodecyl ester (CAS CATO-C4X-116572)
- 1-(Thiazol-2-yl)piperidin-3-amine hydrochloride (CAS 1185309-72-1)
- Palmitoyl Tripeptide-1 TFA salt (CAS 2803375-47-3)
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