Ketoprofen Impurity 115 CAS 72235-46-2
| CAS No. | 72235-46-2 |
| Molecular Formula | C14H10Br2O |
| Molecular Weight | 354.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ketoprofen Impurity 115 is closely related to a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ketoprofen Impurity 115 (CAS 72235-46-2, C14H10Br2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ketoprofen Impurity 115 (C14H10Br2O) contains a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ketoprofen Impurity 115 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10Br2O |
| Molecular Weight | 354.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Br-containing |
Related Ketoprofen Standards
- Ketoprofen Impurity 116 (CAS 1777830-06-4)
- Ketoprofen Impurity 26 (CAS 1777829-91-0)
- Ketoprofen Impurity 60 (CAS 1777830-05-3)
- Ketoprofen Impurity 88 (CAS 1984110-22-6)
- Ketoprofen Impurity 93 (CAS 2733641-85-3)
- Ketoprofen Impurity 94 (CAS CATO-C4X-147194)
- Ketoprofen 2-Ethylhexyl Ester (CAS CATO-C4X-147169)
- Ketoprofen Impurity 68 (CAS CATO-C4X-147168)
Recommended Standards
- 4-(3,5-Dibromobenzyl)benzaldehyde (CAS 2586125-92-8)
- Ethyl 3,3-bis(tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate (CAS 1302132-95-1)
- 2-Bromo-1-(4-bromophenyl)-2-phenylethan-1-one (CAS 24567-06-4)
- 3-(Tetrahydrofuran-2-yl)propyl decanoate (CAS 5453-15-6)
- Bromfenac Impurity 36 (CAS CATO-C4X-200236)
- Phosphoramidite Impurity 27 (CAS CATO-C4X-288627)
- Risdiplam impurity 5 (CAS CATO-C4X-30125)
- 8-Fluoro-7-methyl-5-nitroquinoline-2-carbaldehyde (CAS 1420794-31-5)
- tert-Butyl ((2-formyl-6-(trifluoromethyl)pyridin-4-yl)methyl)carbamate (CAS 1393572-85-4)
- 3-(Benzenesulfonyl)-4,6-dimethyl-2-{[3-(trifluoromethyl)phenyl]sulfanyl}pyridine (CAS 339017-02-6)
- 5-Bromo-2-chloro-N,N-diethylbenzamide (CAS 892019-21-5)
- (R)-2-(o-tolyl)piperidine (CAS 742044-13-9)
- Fondaparinux Sodium Impurity 14 (CAS CATO-C4X-205214)
- DAPK Substrate Peptide (CAS 386769-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com