(4-Chloro-2-fluorophenyl)methanamine CAS 72235-57-5

Purity 97%+In StockPharmaceutical Standards
CAS No.72235-57-5
Molecular FormulaC7H7ClFN
Molecular Weight159.59 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(4-Chloro-2-fluorophenyl)methanamine CAS 72235-57-5 chemical structure

Description

The occurrence of (4-Chloro-2-fluorophenyl)methanamine is closely related to a nitrile group, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(4-Chloro-2-fluorophenyl)methanamine (CAS 72235-57-5), molecular formula C7H7ClFN and molecular weight 159.59 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, fluorine/chlorine substitution, an aromatic ring system, (4-Chloro-2-fluorophenyl)methanamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 159.59 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (4-Chloro-2-fluorophenyl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H7ClFN
Molecular Weight159.59 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1977
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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