1-(2-Chlorobenzyl)pyrrolidine CAS 72249-97-9
| CAS No. | 72249-97-9 |
| Molecular Formula | C11H14ClN |
| Molecular Weight | 195.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(2-Chlorobenzyl)pyrrolidine (CAS 72249-97-9), molecular formula C11H14ClN and molecular weight 195.69 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 1-(2-Chlorobenzyl)pyrrolidine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 195.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H14ClN |
| Molecular Weight | 195.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzyl Standards
- 3-(2-Chlorobenzyl)pyrrolidine (CAS 1003561-98-5)
- 1-(4-Chlorobenzyl)cyclobutan-1-amine (CAS 1017184-77-8)
- n-(4-Chlorobenzyl)-1-cyclopropylmethanamine (CAS 1019506-76-3)
- 3-(3-Chlorobenzyl)pyrrolidine (CAS 1158764-50-1)
- (1-(2-Chlorobenzyl)cyclopropyl)methanamine (CAS 1368693-49-5)
- (1-(4-Chlorobenzyl)cyclopropyl)methanamine (CAS 1368801-43-7)
- 1-(3-Chlorobenzyl)pyrrolidine (CAS 78064-92-3)
- 1-(4-Chlorobenzyl)pyrrolidine (CAS 79089-35-3)
Recommended Standards
- (S)-1-Benzyl-3-chloropyrrolidine (CAS 204973-04-6)
- 1-(2-Chloroethyl)-1,2,3,4-tetrahydroquinoline (CAS 724415-21-8)
- 6-Chloro-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline (CAS 1782490-33-8)
- 1-(2-Chlorophenyl)cyclopentanamine (CAS 856563-66-1)
- 5-((Isopropylamino)methyl)pyridin-3-ylboronic acid hydrochloride (CAS 1425335-02-9)
- (S)-2-Amino-N-cyclopropyl-3-methyl-N-(4-(methylthio)benzyl)butanamide (CAS 1353996-44-7)
- (2R,3R,4R,5R)-5-(4-Benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 160107-14-2)
- 3-(Difluoromethyl)pyridine-4-carboxylic acid (CAS 1211541-32-0)
- 2,5-Dichloro-N-ethylpyridin-4-amine (CAS 2380013-67-0)
- 3-(3-Bromobut-3-en-1-yl)phenyl acetate (CAS 890097-82-2)
- 1-Methyl-4-(phenylsulfamoyl)-1h-pyrrole-2-carboxamide (CAS 1000932-96-6)
- Ethyl 4-chlorothieno[2,3-b]pyridine-5-carboxylate (CAS 59713-58-5)
- 6-Bromo-3-isobutyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1029529-16-5)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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