3-Amino-6-benzyl-N-(2,5-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide CAS 723748-41-2
| CAS No. | 723748-41-2 |
| Molecular Formula | C24H20F3N3O3S |
| Molecular Weight | 487.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-6-benzyl-N-(2,5-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Amino-6-benzyl-N-(2,5-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 723748-41-2), molecular formula C24H20F3N3O3S and molecular weight 487.49 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Amino-6-benzyl-N-(2,5-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 487.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H20F3N3O3S |
| Molecular Weight | 487.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 3-Amino-6-benzyl-N-(3,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 723748-21-8)
- ethyl 1-(6-amino-3-fluoro-5-(3-hydroxyazetidin-1-yl)pyridin-2-yl)-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS CATO-C4X-263726)
- 3-Amino-6-(benzo[d][1,3]dioxol-5-yl)-N-(4-methoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 626227-65-4)
- 2-(4-(2-Amino-3-cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2-ethoxyphenoxy)-N-phenylacetamide (CAS 332053-41-5)
- 2-(4-(2-Amino-3-cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2-methoxyphenoxy)-N-(m-tolyl)acetamide (CAS 336179-99-8)
- 2-(4-(2-Amino-3-cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2-methoxyphenoxy)-N-(o-tolyl)acetamide (CAS 352435-31-5)
- 2-(4-(2-Amino-3-cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromen-4-yl)-2-methoxyphenoxy)-N-(p-tolyl)acetamide (CAS 332053-12-0)
- Ethyl 6-amino-5-cyano-2-[({3-cyano-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-2-yl}sulfanyl)methyl]-4-(pyridin-3-yl)-4H-pyran-3-carboxylate (CAS 625375-71-5)
Recommended Standards
- 3-((4-Methylbenzyl)sulfonyl)-4-phenyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 383145-88-8)
- Vonoprazan Impurity 213 (CAS CATO-C4X-1020213)
- JBJ-03-142-02 (CAS 2068806-31-3)
- CAS 1628530-47-1 (CAS 1628530-47-1)
- 2,4,6-Tribromo-3-nitrophenol (CAS 69076-62-6)
- 4-Methoxypyridine-2,6-dicarbonitrile (CAS 453566-13-7)
- tert-Butyl N-(azepan-4-yl)-N-methylcarbamate (CAS 1408075-96-6)
- 5-Bromo-2-methyl-6-morpholinonicotinic acid (CAS 1443288-75-2)
- 3-Ethyl-5-methoxy-1-methyl-1h-pyrazole-4-carbaldehyde (CAS 1427380-57-1)
- 3,7-Dibromo-10-phenyl-10H-phenothiazine (CAS 89922-58-7)
- Dabsyl-L-leucine (CAS 89131-12-4)
- Meprobamate-D7 (propyl-D7) (CAS 1435933-83-7)
- (1-(1,3,4-Thiadiazol-2-yl)piperidin-4-yl)methanamine (CAS 1339187-84-6)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
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