5-Bromo-2,4-bis((4-nitrobenzyl)thio)pyrimidine CAS 7249-22-1
| CAS No. | 7249-22-1 |
| Molecular Formula | C18H13BrN4O4S2 |
| Molecular Weight | 493.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-2,4-bis((4-nitrobenzyl)thio)pyrimidine is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-2,4-bis((4-nitrobenzyl)thio)pyrimidine (CAS 7249-22-1) is a high-purity analytical reference standard with the molecular formula C18H13BrN4O4S2 and a molecular weight of 493.35 g/mol.
The molecular framework of 5-Bromo-2,4-bis((4-nitrobenzyl)thio)pyrimidine (C18H13BrN4O4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-2,4-bis((4-nitrobenzyl)thio)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13BrN4O4S2 |
| Molecular Weight | 493.35 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Bromo Standards
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Recommended Standards
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- N-(E)-3-Tributyltinallyl-1-naphthalene-d7-methylamine (CAS 1310383-84-6)
- N-(3,4-dichlorophenyl)-4-(4-(3-(trifluoromethyl)phenyl)thiazol-2-yl)benzamide (CAS 338397-04-9)
- ((2R,3S,4R,5R)-5-(6-(2-Acetylbenzamido)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 398133-26-1)
- 1-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde (CAS 878427-46-4)
- 4-((Naphthalen-1-yloxy)methyl)aniline (CAS 212189-28-1)
- N-(2,3-dichlorophenyl)-2-((5-(trifluoromethyl)pyridin-2-yl)thio)acetamide (CAS 303091-22-7)
- 1,2-Dibromodecane (CAS 28467-71-2)
- 2-(dimethylamino)isonicotinonitrile (CAS 80882-52-6)
- N-(2-methyl-6-(pyrrolidin-3-yl)pyridin-4-yl)pyrimidin-2-amine (CAS 1361114-81-9)
- N-((5-(4-methoxyphenyl)-1H-pyrazol-4-yl)methyl)cyclopropanamine (CAS 1423517-28-5)
- Biotin-XX-hydrazide, 98% (CAS 211237-33-1)
- 6-Chloro-2,3-dihydro-imidazo[1,2-b]pyridazine (CAS 24439-00-7)
- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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