N1,N3,N5-Tri(pyridin-4-yl)benzene-1,3,5-tricarboxamide CAS 725274-03-3
| CAS No. | 725274-03-3 |
| Molecular Formula | C24H18N6O3 |
| Molecular Weight | 438.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
N1,N3,N5-Tri(pyridin-4-yl)benzene-1,3,5-tricarboxamide (CAS 725274-03-3) is a high-purity analytical reference standard with the molecular formula C24H18N6O3 and a molecular weight of 438.44 g/mol.
The molecular framework of N1,N3,N5-Tri(pyridin-4-yl)benzene-1,3,5-tricarboxamide (C24H18N6O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), N1,N3,N5-Tri(pyridin-4-yl)benzene-1,3,5-tricarboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18N6O3 |
| Molecular Weight | 438.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 6 |
Recommended Standards
- N1,N3,N5-Tri(pyridin-3-yl)benzene-1,3,5-tricarboxamide (CAS 201036-79-5)
- Candesartan Cilexetil Impurity 46 (CAS 1821386-35-9)
- AMG 837 (CAS 865231-46-5)
- 2-(4-Methoxyphenyl)-4-oxo-4H-chromen-3-yl 4-methoxybenzenesulfonate (CAS 301193-65-7)
- 2-(((Diethoxyphosphoryl)methyl)thio)ethyl acetate (CAS 141650-97-7)
- 3-(Piperazin-1-yl)benzamide dihydrochloride (CAS 807624-16-4)
- 2-Bromo-N-cyclopentyl-2-methylpropanamide (CAS 1225912-27-5)
- 1-[2-(phenylsulfanyl)ethyl]piperazine dihydrochloride (CAS 1172282-69-7)
- 3-Methyl-6,7-dihydro-[1,4]dioxino[2',3':4,5]benzo[1,2-d]thiazol-2(3H)-imine (CAS 1286711-27-0)
- Ethyl 2-oxo-2-(1H-pyrazol-4-yl)acetate (CAS 869557-79-9)
- n-(Cyclopropylmethyl)-2-phenoxyacetamide (CAS 1090505-23-9)
- 3-[6-(aminomethyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2171626-62-1)
- (4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one (CAS 34371-14-7)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
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