Hydrocortisone 17-Butyrate 21-Propionate CAS 72590-77-3
| CAS No. | 72590-77-3 |
| Molecular Formula | C28H40O7 |
| Molecular Weight | 488.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Hydrocortisone 17-Butyrate 21-Propionate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Hydrocortisone 17-Butyrate 21-Propionate (CAS 72590-77-3), a certified reference material (molecular formula C28H40O7, MW 488.61 g/mol) for analytical method development and quality control.
Hydrocortisone 17-Butyrate 21-Propionate (C28H40O7) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H40O7 |
| Molecular Weight | 488.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
Related Hydrocortisone Standards
- Hydrocortisone 17-Valerate,21 Acetate (CAS 81456-46-4)
- Hydrocortisone 11,17,21-Triacetate (CAS 3517-51-9)
- Hydrocortisone 21-Octanoate (CAS 6678-14-4)
- Hydrocortisone impurity 41 (CAS CATO-C4X-140141)
- Hydrocortisone Cypionate (CAS 508-99-6)
- Hydrocortisone Impurity 29 (CAS CATO-C4X-140129)
- Hydrocortisone Impurity 33 (CAS 77106-62-8)
- Hydrocortisone Impurity 45 (CAS 114593-86-1)
Recommended Standards
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