2-Chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]propanamide CAS 726154-28-5
| CAS No. | 726154-28-5 |
| Molecular Formula | C12H9Cl3N2OS |
| Molecular Weight | 335.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 335.64 g/mol gives 2-Chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]propanamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-Chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]propanamide (CAS 726154-28-5), a certified reference material (molecular formula C12H9Cl3N2OS, MW 335.64 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]propanamide (C12H9Cl3N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-N-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]propanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9Cl3N2OS |
| Molecular Weight | 335.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1365961-91-6 2-Chloro-N-[4-(2,4-dichlorophenyl)-1,3-thiazol-2-yl]propanamide MFCD22056587 (CAS 1365961-91-6)
- 2-Chloro-N-[3-(2,4-dichlorobenzyl)thiazol-2(3H)-ylidene]acetamide (CAS 731827-29-5)
- 4-Chloro-2-((2,4-dichlorobenzyl)thio)-5-methoxypyrimidine (CAS 339275-84-2)
- 4-Chloro-2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-5-methoxypyrimidine (CAS 338955-82-1)
- 4-Chloro-2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-methoxypyrimidine (CAS 339275-97-7)
- 2-Chloro-N-cyclopropyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1019918-90-1)
- 1-(3-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperidin-2-one (CAS 2096336-50-2)
- 2-Chloro-N-(cyclopropylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2377609-63-5)
Recommended Standards
- N,N-Diisopropyl-2-(1,1,2,2,2-pentamethyldisilanyl)benzamide (CAS 2204263-18-1)
- N-(2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutanecarboxamide (CAS 2246693-75-2)
- 2-(3-Methylpiperidin-1-yl)-N-(2,4,6-trichlorophenyl)acetamide (CAS 332162-66-0)
- 4-Chloro-N-((perfluorophenyl)methyl)benzamide (CAS 304458-50-2)
- 1-((2-Methoxy-4,5-dimethylphenyl)sulfonyl)piperidine (CAS 457961-73-8)
- 4,6-Dimethoxy-8-((3-methylbut-2-en-1-yl)oxy)furo[2,3-b]quinoline (CAS 651737-85-8)
- Phenyl (R)-((4-methylmorpholin-2-yl)methyl)carbamate (CAS 1268521-43-2)
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- 2-Bromo-5-hydroxynicotinaldehyde (CAS 1289173-26-7)
- 2-(2-Methyl-1h-indol-3-yl)-N-(thiophen-2-ylmethyl)ethan-1-amine hydrochloride (CAS 1049786-30-2)
- 5-Bromo-1-methyl-1H-imidazol-2-amine hydrochloride (CAS 1822966-76-6)
- 9-(tert-Butyl) 3-ethyl (1R,5S)-2-oxo-9-azabicyclo[3.3.1]nonane-3,9-dicarboxylate (CAS 1884387-04-5)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
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