5-Nitro-2-(2,2,2-trifluoro-ethoxy)-pyridine CAS 72617-81-3

Purity 97%+In StockPharmaceutical Standards
CAS No.72617-81-3
Molecular FormulaC7H5F3N2O3
Molecular Weight222.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Nitro-2-(2,2,2-trifluoro-ethoxy)-pyridine CAS 72617-81-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Nitro-2-(2,2,2-trifluoro-ethoxy)-pyridine.

5-Nitro-2-(2,2,2-trifluoro-ethoxy)-pyridine (CAS 72617-81-3), molecular formula C7H5F3N2O3 and molecular weight 222.12 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-Nitro-2-(2,2,2-trifluoro-ethoxy)-pyridine (C7H5F3N2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 5-Nitro-2-(2,2,2-trifluoro-ethoxy)-pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC7H5F3N2O3
Molecular Weight222.12 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1977
Halogen ContentF-containing
Nitrogen Atoms2

Related Nitro Standards

Recommended Standards

Why CATO?