4-((5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol CAS 727386-40-5

Purity 97%+In StockPharmaceutical Standards
CAS No.727386-40-5
Molecular FormulaC14H14N2O4S
Molecular Weight306.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-((5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol CAS 727386-40-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-((5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol.

4-((5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol (CAS 727386-40-5), molecular formula C14H14N2O4S and molecular weight 306.34 g/mol, is a CATO reference standard with documented purity and traceability.

4-((5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol (C14H14N2O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-((5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H14N2O4S
Molecular Weight306.34 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Nitrogen Atoms2
Sulfur Atoms1

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