3-(2-(3-Methoxyphenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid CAS 727652-33-7
| CAS No. | 727652-33-7 |
| Molecular Formula | C18H16N2O3 |
| Molecular Weight | 308.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(2-(3-Methoxyphenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727652-33-7), molecular formula C18H16N2O3 and molecular weight 308.33 g/mol, is a CATO reference standard with documented purity and traceability.
3-(2-(3-Methoxyphenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid (C18H16N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-(2-(3-Methoxyphenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16N2O3 |
| Molecular Weight | 308.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Methoxyphenyl Standards
- [(4-Methoxyphenyl)(2-morpholin-4-yl-2-oxoethyl)-amino]acetic acid (CAS 1142205-62-6)
- Ethyl 2-(4-methoxyphenyl)quinazoline-4-carboxylate (CAS 1446786-17-9)
- (E)-3-(2-(4-methoxyphenyl)-8-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727652-34-8)
- 1-(2-Methoxyphenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-29-7)
- 1-(4-Methoxyphenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-31-1)
- 1-benzyl-3-(2-methoxyphenyl)-1H-pyrazole-4-carboxylic acid (CAS 956354-20-4)
- 1-Benzyl-3-(3-methoxyphenyl)-1h-pyrazole-4-carboxylic acid (CAS 956505-11-6)
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Recommended Standards
- 3-(1-Oxo-4-phenylphthalazin-2(1H)-yl)propanehydrazide (CAS 618443-91-7)
- 3-(2-(4-Methoxyphenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727652-26-8)
- 3-((4-Methoxyphenyl)amino)-6-(p-tolyl)-1,2,4-triazin-5(4H)-one (CAS 881432-60-6)
- 3-(2,5-Dimethoxyphenyl)-1-phenyl-1h-pyrazole-4-carbaldehyde (CAS 956206-42-1)
- Tert-butyl (2-formylquinolin-8-yl)carbamate (CAS 380153-78-6)
- 1-Mesityl-2-(methylthio)ethan-1-one (CAS 1183179-35-2)
- 1',2'-Dihydro-[1,1':3',1'':4'',1'''-quaterphenyl]-6'-carbaldehyde (CAS 951772-77-3)
- (2-Fluoro-4-(3-methylpiperidine-1-carbonyl)phenyl)boronic acid (CAS 2096333-94-5)
- 2,4,6-Triphenylpyridine (CAS 580-35-8)
- 5-Bromo-N-cyclobutyl-2-fluorobenzamide (CAS 1249811-13-9)
- 2'-Methyl-[1,1'-biphenyl]-3-sulfonyl chloride (CAS 1032507-41-7)
- Orforglipron Impurity 50 (CAS CATO-C4X-323450)
- Ruxolitinib Impurity 110 (CAS CATO-C4X-2058110)
- Acetyl Tetrapeptide- 15 (CAS 928007-64-1)
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